PMID- 26648981
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20151209
LR  - 20200930
IS  - 1682-024X (Print)
IS  - 1681-715X (Electronic)
IS  - 1681-715X (Linking)
VI  - 31
IP  - 5
DP  - 2015 Sep-Oct
TI  - Success rates and prognosis of heart valvuloplasty and valve replacement 
      performed for elderly patients.
PG  - 1033-7
LID - 10.12669/pjms.315.7583 [doi]
AB  - OBJECTIVE: To analyze the success rates and prognosis of heart valvuloplasty and 
      valve replacement for elderly patients, and to provide clinical evidence. 
      METHODS: A total of 1240 patients who received heart valve surgeries in our 
      hospital from June 2004 to October 2014 were selected and retrospectively 
      analyzed. They were divided into two groups based on age (60), and those older 
      than 60 (Group B) suffered from rheumatic valvular heart disease and nonrheumatic 
      valvular heart disease including degenerative valve disease. Mitral valve 
      replacement (MVR), tricuspid valve replacement (TVR), aortic valve replacement 
      (AVR), double valve replacement (DVR), mitral valvuloplasty (MVP) and tricuspid 
      valvuloplasty (TVP) were performed by using bioprosthetic and mechanical valves. 
      Before surgery, coronary angiography, coronary artery bypass grafting (CABG), 
      left atrial thrombectomy, left atrial wall folding and radiofrequency ablation 
      were conducted. For the patients younger than 60 (Group A) who had congenital 
      heart disease, rheumatic valvular heart disease and valvular heart disease, MVR, 
      AVR, DVR, MVP, TVP and closed cuspid commissurotomy were performed with 
      bioprosthetic and mechanical valves. The two groups were then monitored. RESULTS: 
      The mortality rates of Group A and Group B were 2.7% (16 cases) and 3.1% (20 
      cases) respectively. They died mainly of malignant ventricular arrhythmias, 
      multiple organ failure, left ventricular rupture, low cardiac output syndrome, 
      acute renal failure, respiratory failure, upper gastrointestinal bleeding, 
      mechanical valve failure and cerebrovascular accident. The two groups had 
      significantly different application rates of bioprosthetic valve, times of 
      auxiliary ventilation and hospitalization stay lengths (P<0.05), but left 
      ventricular ejection fractions, left ventricular end-diastolic diameters 
      (LVEDDs), mortality rates as well as times of aortic cross-clamping and 
      cardiopulmonary bypass were similar (P>0.05). LVEDD, complicated coronary artery 
      disease, CABG and grade of the New York Heart Association Functional 
      Classification were independent risk factors for postoperative death. CONCLUSION: 
      When heart valvuloplasty and valve replacement were performed for elderly 
      patients, the success rate and prognosis could only be improved by optimizing 
      preoperative preparation, shortening the times of cardiopulmonary bypass and 
      aortic cross-clamping, and paying particular attention to myocardial protection 
      and postoperative treatment.
FAU - Liu, Weichao
AU  - Liu W
AD  - Weichao Liu, Department of Cardiothoracic and Vascular Surgery, Huaihe Hospital, 
      Henan University, Kaifeng 475000, Henan Province, P. R. China.
FAU - He, Fei
AU  - He F
AD  - Fei He, Department of Cardiothoracic and Vascular Surgery, Huaihe Hospital, Henan 
      University, Kaifeng 475000, Henan Province, P. R. China.
FAU - Shi, Gongning
AU  - Shi G
AD  - Gongning Shi, Department of Cardiothoracic and Vascular Surgery, Huaihe Hospital, 
      Henan University, Kaifeng 475000, Henan Province, P. R. China.
LA  - eng
PT  - Journal Article
PL  - Pakistan
TA  - Pak J Med Sci
JT  - Pakistan journal of medical sciences
JID - 100913117
PMC - PMC4641250
OTO - NOTNLM
OT  - Elderly
OT  - Heart valve replacement
OT  - Heart valvuloplasty
OT  - Prognosis
OT  - Success rate
EDAT- 2015/12/10 06:00
MHDA- 2015/12/10 06:01
PMCR- 2015/09/01
CRDT- 2015/12/10 06:00
PHST- 2015/12/10 06:00 [entrez]
PHST- 2015/12/10 06:00 [pubmed]
PHST- 2015/12/10 06:01 [medline]
PHST- 2015/09/01 00:00 [pmc-release]
AID - PJMS-31-1033 [pii]
AID - 10.12669/pjms.315.7583 [doi]
PST - ppublish
SO  - Pak J Med Sci. 2015 Sep-Oct;31(5):1033-7. doi: 10.12669/pjms.315.7583.