PMID- 26653172
OWN - NLM
STAT- MEDLINE
DCOM- 20160919
LR  - 20151218
IS  - 1757-6199 (Electronic)
IS  - 1757-6180 (Linking)
VI  - 8
IP  - 2
DP  - 2016
TI  - Development of an Excel-based laboratory information management system for 
      improving workflow efficiencies in early ADME screening.
PG  - 99-110
LID - 10.4155/bio.15.232 [doi]
AB  - BACKGROUND: There is a clear requirement for enhancing laboratory information 
      management during early absorption, distribution, metabolism and excretion (ADME) 
      screening. The application of a commercial laboratory information management 
      system (LIMS) is limited by complexity, insufficient flexibility, high costs and 
      extended timelines. RESULTS: An improved custom in-house LIMS for ADME screening 
      was developed using Excel. All Excel templates were generated through macros and 
      formulae, and information flow was streamlined as much as possible. This system 
      has been successfully applied in task generation, process control and data 
      management, with a reduction in both labor time and human error rates. 
      CONCLUSION: An Excel-based LIMS can provide a simple, flexible and 
      cost/time-saving solution for improving workflow efficiencies in early ADME 
      screening.
FAU - Lu, Xinyan
AU  - Lu X
AD  - Drug Metabolism & Pharmacokinetics, Platform Technology & Science, 
      GlaxoSmithKline R&D, Shanghai 201203, China.
LA  - eng
PT  - Journal Article
DEP - 20151210
PL  - England
TA  - Bioanalysis
JT  - Bioanalysis
JID - 101512484
RN  - 0 (Pharmaceutical Preparations)
SB  - IM
MH  - *Absorption, Physicochemical
MH  - Drug Evaluation, Preclinical/*methods
MH  - Information Management/*methods
MH  - *Laboratories
MH  - Pharmaceutical Preparations/chemistry/*metabolism
MH  - *Software
MH  - *Workflow
EDAT- 2015/12/15 06:00
MHDA- 2016/09/20 06:00
CRDT- 2015/12/15 06:00
PHST- 2015/12/15 06:00 [entrez]
PHST- 2015/12/15 06:00 [pubmed]
PHST- 2016/09/20 06:00 [medline]
AID - 10.4155/bio.15.232 [doi]
PST - ppublish
SO  - Bioanalysis. 2016;8(2):99-110. doi: 10.4155/bio.15.232. Epub 2015 Dec 10.