PMID- 26666508
OWN - NLM
STAT- MEDLINE
DCOM- 20170313
LR  - 20210528
IS  - 1476-5624 (Electronic)
IS  - 1362-4393 (Print)
IS  - 1362-4393 (Linking)
VI  - 54
IP  - 9
DP  - 2016 Sep
TI  - Effects of aerobic exercise training on fitness and walking-related outcomes in 
      ambulatory individuals with chronic incomplete spinal cord injury.
PG  - 675-81
LID - 10.1038/sc.2015.212 [doi]
AB  - STUDY DESIGN: Single group, pretest-post-test study. OBJECTIVES: To determine the 
      effects of a non-task-specific, voluntary, progressive aerobic exercise training 
      (AET) intervention on fitness and walking-related outcomes in ambulatory adults 
      with chronic motor-incomplete SCI. SETTING: Rehabilitation research center. 
      METHODS: Ten ambulatory individuals (50% female; 57.94+/-9.33 years old; 11.11+/-9.66 
      years postinjury) completed voluntary, progressive moderate-to-vigorous intensity 
      AET on a recumbent stepper 3 days per week for 6 weeks. The primary outcome 
      measures were aerobic capacity (VO2peak (volume of oxygen that the body can use 
      during physical exertion)) and self-selected overground walking speed (OGWS). 
      Secondary outcome measures included walking economy, 6-minute walk test (6MWT), 
      daily step counts, Walking Index for Spinal Cord Injury (WISCI-II), Dynamic Gait 
      Index (DGI) and Berg Balance Scale (BBS). RESULTS: Nine participants completed 
      all testing and training. Significant improvements in aerobic capacity (P=0.011), 
      OGWS (P=0.023), the percentage of VO2peak used while walking at self-selected 
      speed (P=0.03) and daily step counts (P=0.025) resulted following training. 
      CONCLUSIONS: The results indicate that total-body, voluntary, progressive AET is 
      safe, feasible, and effective for improving aerobic capacity, walking speed, and 
      select walking-related outcomes in an exclusively ambulatory SCI sample. This 
      study suggests the potential for non-task-specific aerobic exercise to improve 
      walking following incomplete SCI and builds a foundation for further 
      investigation aimed at the development of exercise based rehabilitation 
      strategies to target functionally limiting impairments in ambulatory individuals 
      with chronic SCI.
FAU - DiPiro, N D
AU  - DiPiro ND
AD  - Department of Health Sciences and Research, Medical University of South Carolina, 
      Charleston, SC, USA.
FAU - Embry, A E
AU  - Embry AE
AD  - Department of Health Sciences and Research, Medical University of South Carolina, 
      Charleston, SC, USA.
AD  - Division of Physical Therapy, Medical University of South Carolina, Charleston, 
      SC, USA.
AD  - Ralph H Johnson VAMC, Charleston, SC, USA.
FAU - Fritz, S L
AU  - Fritz SL
AD  - Department of Exercise Science, Physical Therapy Program, University of South 
      Carolina, Columbia, SC, USA.
FAU - Middleton, A
AU  - Middleton A
AD  - Department of Exercise Science, Physical Therapy Program, University of South 
      Carolina, Columbia, SC, USA.
FAU - Krause, J S
AU  - Krause JS
AD  - Department of Health Sciences and Research, Medical University of South Carolina, 
      Charleston, SC, USA.
FAU - Gregory, C M
AU  - Gregory CM
AD  - Department of Health Sciences and Research, Medical University of South Carolina, 
      Charleston, SC, USA.
AD  - Division of Physical Therapy, Medical University of South Carolina, Charleston, 
      SC, USA.
AD  - Ralph H Johnson VAMC, Charleston, SC, USA.
LA  - eng
GR  - P20 GM109040/GM/NIGMS NIH HHS/United States
GR  - T32 GM081740/GM/NIGMS NIH HHS/United States
GR  - TL1 TR000061/TR/NCATS NIH HHS/United States
GR  - UL1 TR000062/TR/NCATS NIH HHS/United States
PT  - Journal Article
DEP - 20151215
PL  - England
TA  - Spinal Cord
JT  - Spinal cord
JID - 9609749
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Chronic Disease
MH  - Disability Evaluation
MH  - Exercise/*physiology
MH  - Exercise Therapy/*methods
MH  - Female
MH  - Gait Disorders, Neurologic/*etiology/*rehabilitation
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Recovery of Function
MH  - Rehabilitation Centers
MH  - Spinal Cord Injuries/*complications/rehabilitation
MH  - Statistics, Nonparametric
MH  - Trauma Severity Indices
MH  - Treatment Outcome
MH  - Walking
MH  - Young Adult
PMC - PMC4909592
MID - NIHMS734581
EDAT- 2015/12/17 06:00
MHDA- 2017/03/14 06:00
PMCR- 2016/06/15
CRDT- 2015/12/16 06:00
PHST- 2015/07/10 00:00 [received]
PHST- 2015/10/29 00:00 [revised]
PHST- 2015/10/30 00:00 [accepted]
PHST- 2015/12/16 06:00 [entrez]
PHST- 2015/12/17 06:00 [pubmed]
PHST- 2017/03/14 06:00 [medline]
PHST- 2016/06/15 00:00 [pmc-release]
AID - sc2015212 [pii]
AID - 10.1038/sc.2015.212 [doi]
PST - ppublish
SO  - Spinal Cord. 2016 Sep;54(9):675-81. doi: 10.1038/sc.2015.212. Epub 2015 Dec 15.