PMID- 26668513
OWN - NLM
STAT- MEDLINE
DCOM- 20161107
LR  - 20220419
IS  - 2219-2840 (Electronic)
IS  - 1007-9327 (Print)
IS  - 1007-9327 (Linking)
VI  - 21
IP  - 45
DP  - 2015 Dec 7
TI  - Comparison of Stretta procedure and toupet fundoplication for gastroesophageal 
      reflux disease-related extra-esophageal symptoms.
PG  - 12882-7
LID - 10.3748/wjg.v21.i45.12882 [doi]
AB  - AIM: To compare the outcomes between the Stretta procedure and laparoscopic 
      toupet fundoplication (LTF) in patients with gastroesophageal reflux disease 
      (GERD)-related extra-esophageal symptoms. METHODS: From January 2011 to February 
      2012, a total of 98 patients diagnosed with GERD-related extra-esophageal 
      symptoms who met the inclusion criteria were enrolled in this study. All patients 
      who either underwent the Stretta procedure or LTF treatment have now completed 
      the 3-year follow-up. Primary outcome measures, including frequency and severity 
      of extra-esophageal symptoms, proton pump inhibitor (PPI) use, satisfaction, and 
      postoperative complications, were assessed. The results of the Stretta procedure 
      and LTF therapy were analyzed and compared. RESULTS: There were 47 patients in 
      the Stretta group and 51 patients in the LTF group. Ninety patients were 
      available at the 3-year follow-up. The total of the frequency and severity scores 
      for every symptom improved in both groups (P < 0.05). Improvement in symptom 
      scores of cough, sputum, and wheezing did not achieve statistical significance 
      between the two groups (P > 0.05). However, the score for globus hysterics was 
      different between the Stretta group and the LTF group (4.9 +/- 2.24 vs 3.2 +/- 2.63, 
      P < 0.05). After the Stretta procedure and LTF treatment, 29 and 33 patients in 
      each group achieved PPI therapy independence (61.7% vs 64.7%, P = 0.835). The 
      patients in the LTF group were more satisfied with their quality of life than 
      those in the Stretta procedure group (P < 0.05). Most complications resolved 
      without intervention within two weeks; however, two patients in the LTF group 
      still suffered from severe dysphagia 2 wk after the operation, and it improved 
      after bougie dilation treatment in both patients. CONCLUSION: The Stretta 
      procedure and LTF were both safe and effective for the control of GERD-related 
      extra-esophageal symptoms and the reduction of PPI use.
FAU - Yan, Chao
AU  - Yan C
AD  - Chao Yan, Wei-Tao Liang, Zhong-Gao Wang, Zhi-Wei Hu, Ji-Min Wu, Mei-Ping Chen, 
      Department of Gastroesophageal Reflux Disease, Second Artillery General Hospital 
      of Chinese People's Liberation Army, Beijing 100088, China.
FAU - Liang, Wei-Tao
AU  - Liang WT
AD  - Chao Yan, Wei-Tao Liang, Zhong-Gao Wang, Zhi-Wei Hu, Ji-Min Wu, Mei-Ping Chen, 
      Department of Gastroesophageal Reflux Disease, Second Artillery General Hospital 
      of Chinese People's Liberation Army, Beijing 100088, China.
FAU - Wang, Zhong-Gao
AU  - Wang ZG
AD  - Chao Yan, Wei-Tao Liang, Zhong-Gao Wang, Zhi-Wei Hu, Ji-Min Wu, Mei-Ping Chen, 
      Department of Gastroesophageal Reflux Disease, Second Artillery General Hospital 
      of Chinese People's Liberation Army, Beijing 100088, China.
FAU - Hu, Zhi-Wei
AU  - Hu ZW
AD  - Chao Yan, Wei-Tao Liang, Zhong-Gao Wang, Zhi-Wei Hu, Ji-Min Wu, Mei-Ping Chen, 
      Department of Gastroesophageal Reflux Disease, Second Artillery General Hospital 
      of Chinese People's Liberation Army, Beijing 100088, China.
FAU - Wu, Ji-Min
AU  - Wu JM
AD  - Chao Yan, Wei-Tao Liang, Zhong-Gao Wang, Zhi-Wei Hu, Ji-Min Wu, Mei-Ping Chen, 
      Department of Gastroesophageal Reflux Disease, Second Artillery General Hospital 
      of Chinese People's Liberation Army, Beijing 100088, China.
FAU - Zhang, Chao
AU  - Zhang C
AD  - Chao Yan, Wei-Tao Liang, Zhong-Gao Wang, Zhi-Wei Hu, Ji-Min Wu, Mei-Ping Chen, 
      Department of Gastroesophageal Reflux Disease, Second Artillery General Hospital 
      of Chinese People's Liberation Army, Beijing 100088, China.
FAU - Chen, Mei-Ping
AU  - Chen MP
AD  - Chao Yan, Wei-Tao Liang, Zhong-Gao Wang, Zhi-Wei Hu, Ji-Min Wu, Mei-Ping Chen, 
      Department of Gastroesophageal Reflux Disease, Second Artillery General Hospital 
      of Chinese People's Liberation Army, Beijing 100088, China.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - World J Gastroenterol
JT  - World journal of gastroenterology
JID - 100883448
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Catheter Ablation/adverse effects
MH  - Female
MH  - Fundoplication/adverse effects/*methods
MH  - Gastroesophageal Reflux/complications/diagnosis/*surgery
MH  - Humans
MH  - *Laparoscopy/adverse effects
MH  - Male
MH  - Middle Aged
MH  - Patient Satisfaction
MH  - Postoperative Complications/etiology
MH  - Prospective Studies
MH  - Proton Pump Inhibitors/therapeutic use
MH  - Severity of Illness Index
MH  - Time Factors
MH  - Treatment Outcome
PMC - PMC4671044
OTO - NOTNLM
OT  - Extra-esophageal symptoms
OT  - Gastroesophageal reflux disease
OT  - Laparoscopic Toupet fundoplication
OT  - Proton pump inhibitor use
OT  - Stretta procedure
EDAT- 2015/12/17 06:00
MHDA- 2016/11/08 06:00
PMCR- 2015/12/07
CRDT- 2015/12/16 06:00
PHST- 2015/05/18 00:00 [received]
PHST- 2015/08/09 00:00 [revised]
PHST- 2015/09/30 00:00 [accepted]
PHST- 2015/12/16 06:00 [entrez]
PHST- 2015/12/17 06:00 [pubmed]
PHST- 2016/11/08 06:00 [medline]
PHST- 2015/12/07 00:00 [pmc-release]
AID - 10.3748/wjg.v21.i45.12882 [doi]
PST - ppublish
SO  - World J Gastroenterol. 2015 Dec 7;21(45):12882-7. doi: 10.3748/wjg.v21.i45.12882.