PMID- 26671587
OWN - NLM
STAT- MEDLINE
DCOM- 20170119
LR  - 20220410
IS  - 1130-0108 (Print)
IS  - 1130-0108 (Linking)
VI  - 107
IP  - 12
DP  - 2015 Dec
TI  - Incidence, clinical outcomes, and therapeutic approaches of capsule 
      endoscopy-related adverse events in a large study population.
PG  - 745-52
AB  - INTRODUCTION: Capsule endoscopy (CE) has become a first-line tool for small bowel 
      (SB) examination. However, adverse events (AEs), such as CE retention or 
      aspiration, may occur. The aims of this study were to evaluate incidence, 
      clinical outcomes and therapeutic approaches of CE-related AEs in the largest 
      series published to date. METHODS: Data from 5428 procedures performed at 12 
      institutions between August 2001 and January 2012 were retrospectively analyzed. 
      Baseline patient characteristics; procedure; type, localization and symptoms 
      before/after AEs; previous patency tests performed; therapeutic management and 
      patient's outcome were recorded. RESULTS: The overall incidence of CE-related AEs 
      was 1.9%: 2.0% for SB, 0.9% for esophageal and 0.5% for colon CE. The incidence 
      of capsule retention was significantly higher than capsule aspiration (1.87% vs. 
      0.003%; p < 0.05), in patients suffering from inflammatory bowel disease (IBD) 
      than in obscure GI bleeding (OGIB) (3.3% vs. 1.5%; p < 0.05) and in patients with 
      the combination of nausea/vomiting, abdominal pain and distension. The SB was the 
      most frequent localization of retention (88.2%). The use of patency tests -except 
      for Patency(c) capsule- before CE was not a good predictor for AEs. Most of the 
      patients with AEs developed no or mild symptoms (97%) and were managed by 
      non-surgical methods (64.4%). CONCLUSIONS: CE-related AEs are uncommon and 
      difficult to predict by imagiological examinations. SB retention, that is usually 
      asymptomatic, is the most frequent AE. In absence of symptoms, non-surgical 
      management of CE-related AEs is recommended.
FAU - Fernandez-Urien, Ignacio
AU  - Fernandez-Urien I
AD  - Digestivo, Complejo Hospitalario de Navarra, Espana.
FAU - Carretero, Cristina
AU  - Carretero C
AD  - Universidad de Navarra.
FAU - Gonzalez, Begona
AU  - Gonzalez B
AD  - Hospital Clinic. Barcelona.
FAU - Pons, Vicente
AU  - Pons V
AD  - Hospital Universitario y Politecnico La Fe. Valencia.
FAU - Caunedo, Angel
AU  - Caunedo A
AD  - Hospital Universitario Virgen Macarena. Sevilla.
FAU - Valle, Julio
AU  - Valle J
AD  - Complejo Hospitalario de Toledo. Toledo.
FAU - Redondo-Cerezo, Eduardo
AU  - Redondo-Cerezo E
AD  - Hospital Virgen de las Nieves. Granada.
FAU - Lopez-Higueras, Antonio
AU  - Lopez-Higueras A
AD  - Hospital General Universitario Morales Meseguer. Murcia.
FAU - Valdes, Mariano
AU  - Valdes M
AD  - Hospital Universitario Virgen de la Arrixaca. Murcia.
FAU - Menchen, Pedro
AU  - Menchen P
AD  - Hospital General Universitario Gregorio Maranon Hospital. Madrid.
FAU - Fernandez, Pedro
AU  - Fernandez P
AD  - . Hospital Universitario Marques de Valdecilla. Santander.
FAU - Munoz-Navas, Miguel
AU  - Munoz-Navas M
AD  - Universidad de Navarra.
FAU - Jimenez, Javier
AU  - Jimenez J
AD  - Complejo Hospital de Pamplona. Navarra.
FAU - Herrerias, Juan Manuel
AU  - Herrerias JM
AD  - Hospital Universitario Virgen Macarena. Sevilla.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - Spain
TA  - Rev Esp Enferm Dig
JT  - Revista espanola de enfermedades digestivas
JID - 9007566
SB  - IM
CIN - Rev Esp Enferm Dig. 2015 Dec;107(12 ):711-2. PMID: 26671583
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Capsule Endoscopy/*adverse effects/instrumentation
MH  - Female
MH  - Foreign Bodies/epidemiology/*etiology/therapy
MH  - Humans
MH  - Incidence
MH  - Intestine, Small/*diagnostic imaging
MH  - Male
MH  - Middle Aged
MH  - Respiratory Aspiration/epidemiology/*etiology/therapy
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Spain
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2015/12/17 06:00
MHDA- 2017/01/20 06:00
CRDT- 2015/12/17 06:00
PHST- 2015/12/17 06:00 [entrez]
PHST- 2015/12/17 06:00 [pubmed]
PHST- 2017/01/20 06:00 [medline]
AID - 10.17235/reed.2015.3820/2015 [doi]
PST - ppublish
SO  - Rev Esp Enferm Dig. 2015 Dec;107(12):745-52. doi: 10.17235/reed.2015.3820/2015.