PMID- 26681293
OWN - NLM
STAT- MEDLINE
DCOM- 20171109
LR  - 20190131
IS  - 1470-2738 (Electronic)
IS  - 0143-005X (Print)
IS  - 0143-005X (Linking)
VI  - 70
IP  - 6
DP  - 2016 Jun
TI  - Socioeconomic status, comorbidity and mortality in patients with type 2 diabetes 
      mellitus in Scotland 2004-2011: a cohort study.
PG  - 596-601
LID - 10.1136/jech-2015-206702 [doi]
AB  - BACKGROUND: Mortality in people with and without diabetes often exhibits marked 
      social patterning, risk of death being greater in deprived groups. This may 
      reflect deprivation-related differences in comorbid disease (conditions 
      additional to diabetes itself). This study sought to determine whether the social 
      patterning of mortality in a population with type 2 diabetes mellitus (T2DM) is 
      explained by differential comorbidity. METHODS: Hospital records for 70 197 men 
      and 56 451 women diagnosed with T2DM at 25 years of age and above in Scotland 
      during the period 2004-2011 were used to construct comorbidity histories. 
      Sex-specific logistic models were fitted to predict mortality at 1 year after 
      diagnosis with T2DM, predicted initially by age and socioeconomic status (SES) 
      then extended to incorporate in turn 5 representations of comorbidity (including 
      the Charlson Index). The capacity of comorbidity to explain social mortality 
      gradients was assessed by observing the change in regression coefficients for SES 
      following the addition of comorbidity. RESULTS: After adjustment for age and 
      Charlson Index, the OR for the contrast between the least deprived and most 
      deprived quintiles of SES for men was 0.79 (95% CI 0.67 to 0.94). For women, the 
      OR was 0.81 (0.67 to 0.97). Similar results were obtained for the 4 other 
      comorbidity measures used. CONCLUSIONS: The social patterning of mortality in 
      people with T2DM is not fully explained by differing levels of comorbid disease 
      additional to T2DM itself. Other dimensions of deprivation are implicated in the 
      elevated death rates observed in deprived groups of people with T2DM.
CI  - Published by the BMJ Publishing Group Limited. For permission to use (where not 
      already granted under a licence) please go to 
      http://www.bmj.com/company/products-services/rights-and-licensing/
FAU - Walker, Jeremy
AU  - Walker J
AD  - Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, 
      UK.
FAU - Halbesma, Nynke
AU  - Halbesma N
AD  - Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, 
      UK.
FAU - Lone, Nazir
AU  - Lone N
AD  - Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, 
      UK.
FAU - McAllister, David
AU  - McAllister D
AD  - Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, 
      UK.
FAU - Weir, Christopher J
AU  - Weir CJ
AD  - Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, 
      UK.
FAU - Wild, Sarah H
AU  - Wild SH
AD  - Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, 
      UK.
CN  - Scottish Diabetes Research Network Epidemiology Group
LA  - eng
GR  - CZH/4/922/Chief Scientist Office/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20151217
PL  - England
TA  - J Epidemiol Community Health
JT  - Journal of epidemiology and community health
JID - 7909766
SB  - IM
MH  - *Comorbidity
MH  - Diabetes Mellitus, Type 2/*mortality
MH  - Humans
MH  - Male
MH  - Population Surveillance
MH  - Prevalence
MH  - Scotland/epidemiology
MH  - *Social Class
PMC - PMC4893140
OTO - NOTNLM
OT  - DEPRIVATION
OT  - DIABETES
OT  - EPIDEMIOLOGY
EDAT- 2015/12/19 06:00
MHDA- 2017/11/10 06:00
PMCR- 2016/06/04
CRDT- 2015/12/19 06:00
PHST- 2015/09/25 00:00 [received]
PHST- 2015/11/29 00:00 [accepted]
PHST- 2015/12/19 06:00 [entrez]
PHST- 2015/12/19 06:00 [pubmed]
PHST- 2017/11/10 06:00 [medline]
PHST- 2016/06/04 00:00 [pmc-release]
AID - jech-2015-206702 [pii]
AID - 10.1136/jech-2015-206702 [doi]
PST - ppublish
SO  - J Epidemiol Community Health. 2016 Jun;70(6):596-601. doi: 
      10.1136/jech-2015-206702. Epub 2015 Dec 17.