PMID- 26688922
OWN - NLM
STAT- MEDLINE
DCOM- 20160202
LR  - 20191113
IS  - 0022-9040 (Print)
IS  - 0022-9040 (Linking)
VI  - 55
IP  - 7
DP  - 2015
TI  - [Rate of Detection of Atherosclerosis in Patients With ST Elevation Myocardial 
      Infarction and Concomitant Chronic Obstructive Pulmonary Disease of Light or 
      Moderate Degree of Severity].
PG  - 26-31
AB  - PURPOSE: to study frequency of detection of atherosclerosis among patients with 
      ST elevation myocardial infarction (STEMI) and concomitant chronic obstructive 
      pulmonary disease (COPD) of light or moderate degree of severity, and to 
      elucidate its relation to lung function and level of C-reactive protein (CRP). 
      MATERIAL AND METHODS: STEMI patients (n = 154) were enrolled into 2 groups: with 
      (n = 58, group 1) and without (n = 96, group 2) COPD of light or moderate degree 
      of severity. Examination of all patients included pulmonary function tests, color 
      duplex scanning of arteries, determination of C-reactive protein using high 
      sensitive assay (hs CRP) on days 10-14 from STEMI onset. RESULTS: Group 1 
      patients often had multivessel coronary lesions and signs of multifocal 
      atherosclerosis (MFA).The extent of peripheral artery disease negatively 
      correlated with parameters of lung expiratory function. Patients of this group 
      had higher levels of hs CRP. At the same time STEMI and COPD patients 
      demonstrated higher CRP levels, which reflected the activity of inflammation--one 
      of mechanisms of atherosclerosis development. CONCLUSION: In patients with STEMI 
      and COPD of light or moderate severity impairment of expiratory lung function and 
      elevated level of hs CRP are associated with the presence of multifocal 
      atherosclerosis and hemodynamically significant lesions in arteries.
FAU - Polikutina, O M
AU  - Polikutina OM
FAU - Slepynina, Yu S
AU  - Slepynina YS
FAU - Bazdyrev, E D
AU  - Bazdyrev ED
FAU - Karetnikova, V L
AU  - Karetnikova VL
FAU - Barbarash, O L
AU  - Barbarash OL
LA  - rus
PT  - English Abstract
PT  - Journal Article
PL  - Russia (Federation)
TA  - Kardiologiia
JT  - Kardiologiia
JID - 0376351
SB  - IM
MH  - Aged
MH  - Atherosclerosis/*diagnosis/epidemiology
MH  - Comorbidity
MH  - Diagnosis, Differential
MH  - *Diagnostic Techniques, Cardiovascular
MH  - *Electrocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/diagnosis/*epidemiology/physiopathology
MH  - Pulmonary Disease, Chronic Obstructive/diagnosis/*epidemiology/physiopathology
MH  - Reproducibility of Results
MH  - Respiratory Function Tests
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Siberia/epidemiology
EDAT- 2015/12/23 06:00
MHDA- 2016/02/03 06:00
CRDT- 2015/12/23 06:00
PHST- 2015/12/23 06:00 [entrez]
PHST- 2015/12/23 06:00 [pubmed]
PHST- 2016/02/03 06:00 [medline]
AID - 10.18565/cardio.2015.7.26-31 [doi]
PST - ppublish
SO  - Kardiologiia. 2015;55(7):26-31. doi: 10.18565/cardio.2015.7.26-31.