PMID- 26689451
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20220331
IS  - 1873-460X (Electronic)
IS  - 1056-8727 (Linking)
VI  - 30
IP  - 2
DP  - 2016 Mar
TI  - Obesity and glycemic control in patients with diabetes mellitus: Analysis of 
      physician electronic health records in the US from 2009-2011.
PG  - 212-20
LID - S1056-8727(15)00454-7 [pii]
LID - 10.1016/j.jdiacomp.2015.11.016 [doi]
AB  - AIMS: Examine the association between obesity and glycemic control among patients 
      with type 1 (T1DM) or type 2 diabetes mellitus (T2DM). METHODS: Data from US 
      physician electronic health records (Humedica(R)) from 2009-2011 were utilized. 
      Patients were defined as having above-target glycemic control if they had an 
      HbA1c >/=7% at any time during the study period. Multinomial logistic regressions 
      were conducted separately for T1DM and T2DM patients, and examined associations 
      between BMI categories and probability of having above-target glycemic control 
      (>/=7% and <8%, >/=8% and <9%, or >/=9%) while controlling for patient demographics, 
      general health, comorbid conditions, and antihyperglycemic medication use. 
      RESULTS: There were 14,028 T1DM and 248,567 T2DM patients; 47.8% of T1DM and 
      63.4% of T2DM were obese (BMI >/=30kg/m(2)). For T1DM, being overweight (BMI 
      25-<30), obese class I (30-<35), II (35-<40), or III (>/=40) was associated with a 
      significantly higher probability of having HbA1c>/=8% and <9% or >/=9%, while being 
      overweight was associated with a significantly higher probability of having HbA1c 
      >/=7% and <8% compared to normal BMI (BMI>/=18.5 and<25). For T2DM patients, being 
      overweight, obese class I, II, or III was associated with a significantly higher 
      probability of having HbA1c >/=7% and <8%, >/=8% and <9%, or >/=9%. CONCLUSIONS: For 
      both T1DM and T2DM patients, there were positive and statistically significant 
      associations between being overweight or obese and having suboptimal glycemic 
      control. These findings quantify the associations between obesity and glycemic 
      control, and highlight the potential importance of individual characteristics on 
      glycemic control.
CI  - Copyright (c) 2016 The Authors. Published by Elsevier Inc. All rights reserved.
FAU - Bae, J P
AU  - Bae JP
AD  - Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285. Electronic 
      address: bae_jay@lilly.com.
FAU - Lage, M J
AU  - Lage MJ
AD  - Managing Member, HealthMetrics Outcomes Research, 27576 River Reach Drive, Bonita 
      Springs FL 34134. Electronic address: elagemj@hlthmetrics.com.
FAU - Mo, D
AU  - Mo D
AD  - Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285. Electronic 
      address: mo_daojun@lilly.com.
FAU - Nelson, D R
AU  - Nelson DR
AD  - Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285. Electronic 
      address: nelson_david_r@lilly.com.
FAU - Hoogwerf, B J
AU  - Hoogwerf BJ
AD  - Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285. Electronic 
      address: hoogwerf_byron_james@lilly.com.
LA  - eng
PT  - Journal Article
DEP - 20151117
PL  - United States
TA  - J Diabetes Complications
JT  - Journal of diabetes and its complications
JID - 9204583
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Glucose/*metabolism
MH  - Body Mass Index
MH  - Cohort Studies
MH  - Databases, Factual/statistics & numerical data
MH  - Diabetes Mellitus, Type 1/blood/complications/*epidemiology
MH  - Diabetes Mellitus, Type 2/blood/complications/*epidemiology
MH  - Electronic Health Records/*statistics & numerical data
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Obesity/blood/complications/*epidemiology
MH  - Physicians
MH  - United States/epidemiology
OTO - NOTNLM
OT  - Database research
OT  - Glycemic control
OT  - Obesity therapy
OT  - Type 1 diabetes
OT  - Type 2 diabetes
EDAT- 2015/12/23 06:00
MHDA- 2016/12/15 06:00
CRDT- 2015/12/23 06:00
PHST- 2015/04/09 00:00 [received]
PHST- 2015/11/13 00:00 [revised]
PHST- 2015/11/15 00:00 [accepted]
PHST- 2015/12/23 06:00 [entrez]
PHST- 2015/12/23 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - S1056-8727(15)00454-7 [pii]
AID - 10.1016/j.jdiacomp.2015.11.016 [doi]
PST - ppublish
SO  - J Diabetes Complications. 2016 Mar;30(2):212-20. doi: 
      10.1016/j.jdiacomp.2015.11.016. Epub 2015 Nov 17.