PMID- 26695814
OWN - NLM
STAT- MEDLINE
DCOM- 20170414
LR  - 20181113
IS  - 1741-0444 (Electronic)
IS  - 0140-0118 (Linking)
VI  - 54
IP  - 10
DP  - 2016 Oct
TI  - Monitoring reduced scattering coefficient in pedicle screw insertion trajectory 
      using near-infrared spectroscopy.
PG  - 1533-9
LID - 10.1007/s11517-015-1428-y [doi]
AB  - Pedicle screw (PS) implantation is an ideal treatment for severe multilevel 
      vertebra instabilities. The accuracy of fixating PS is a key factor of spinal 
      surgery. We developed a near-infrared spectroscopy device with a needlelike 
      optical fiber probe to monitor optical parameters (reduced scattering 
      coefficient) of vertebra models in real time. The fresh-frozen cadaver, cats and 
      porcine vertebras were first studied in the experiments. Moreover, the reduced 
      scattering coefficient (mu' s) along the different trajectories of PS insertion 
      was obtained. In the fresh-frozen cadavera experiment, mu' s values could be used 
      to distinguish the different compositions of the thoracic vertebra. In cat 
      vertebra experiment, mu' s values of vertebrae bones, including cortical bone 
      (15.30 +/- 0.18 cm(-1)), cancellous bone (7.84 +/- 1.11 cm(-1)) and spinal cord 
      (19.46 +/- 0.21 cm(-1)), were different in vivo. In the pig vertebrae experiment, 
      there were obvious differences between the normal and abnormal PS puncture curves 
      based on mu' s values. Thus, mu' s values measured by using the proposed device 
      could be used as the pattern factor in spinal fusion surgery. Our studies 
      demonstrate that near-infrared spectroscopy method may be potentially used for 
      assisting the PS insertion.
FAU - Li, Weitao
AU  - Li W
AUID- ORCID: 0000-0001-7855-428X
AD  - Department of Biomedical Engineering, Nanjing University of Aeronautics and 
      Astronautics, Yudao Street 29, Nanjing, 210016, China. liweitao@nuaa.edu.cn.
FAU - Liu, Yangyang
AU  - Liu Y
AD  - Department of Biomedical Engineering, Nanjing University of Aeronautics and 
      Astronautics, Yudao Street 29, Nanjing, 210016, China.
FAU - Sun, Haixiang
AU  - Sun H
AD  - Department of Biomedical Engineering, Nanjing University of Aeronautics and 
      Astronautics, Yudao Street 29, Nanjing, 210016, China.
FAU - Pan, Yue
AU  - Pan Y
AD  - Department of Biomedical Engineering, Nanjing University of Aeronautics and 
      Astronautics, Yudao Street 29, Nanjing, 210016, China.
FAU - Qian, Zhiyu
AU  - Qian Z
AD  - Department of Biomedical Engineering, Nanjing University of Aeronautics and 
      Astronautics, Yudao Street 29, Nanjing, 210016, China.
LA  - eng
PT  - Journal Article
DEP - 20151222
PL  - United States
TA  - Med Biol Eng Comput
JT  - Medical & biological engineering & computing
JID - 7704869
SB  - IM
MH  - Animals
MH  - Cats
MH  - *Pedicle Screws
MH  - Spectroscopy, Near-Infrared/*methods
MH  - Spine
MH  - Swine
OTO - NOTNLM
OT  - Near-infrared
OT  - Pedicle screw
OT  - Reduced scattering coefficient
OT  - Spectroscopy
EDAT- 2015/12/24 06:00
MHDA- 2017/04/15 06:00
CRDT- 2015/12/24 06:00
PHST- 2015/04/20 00:00 [received]
PHST- 2015/12/07 00:00 [accepted]
PHST- 2015/12/24 06:00 [entrez]
PHST- 2015/12/24 06:00 [pubmed]
PHST- 2017/04/15 06:00 [medline]
AID - 10.1007/s11517-015-1428-y [pii]
AID - 10.1007/s11517-015-1428-y [doi]
PST - ppublish
SO  - Med Biol Eng Comput. 2016 Oct;54(10):1533-9. doi: 10.1007/s11517-015-1428-y. Epub 
      2015 Dec 22.