PMID- 26698271
OWN - NLM
STAT- MEDLINE
DCOM- 20170112
LR  - 20220318
IS  - 2169-141X (Electronic)
IS  - 2169-1401 (Linking)
VI  - 44
IP  - 8
DP  - 2016 Dec
TI  - A strategic approach for rapid synthesis of gold and silver nanoparticles by 
      Panax ginseng leaves.
PG  - 1949-1957
AB  - The study highlights the synthesis of gold nanoparticles and silver nanoparticles 
      by fresh leaves of Panax ginseng, an herbal medicinal plant. The reduction of 
      auric chloride and silver nitrate led to the formation of gold and silver 
      nanoparticles within 3 and 45 min, at 80 degrees C, respectively. The developed 
      methodology was rapid, facile, ecofriendly and the utmost significant is quite 
      economical, which did not require subsequent processing for reduction or 
      stabilization of nanoparticles. The nanoparticles were further characterized by 
      Ultraviolet-visible spectroscopy (UV-vis) which showed the relevant peak for gold 
      and silver nanoparticles at 578 and 420 nm, correspondingly. Field-emission 
      transmission electron microscopy (FE-TEM) displayed the spherical shape of 
      monodispersed nanoparticles. FE-TEM revealed that the gold nanoparticles were 
      10-20 nm and silver nanoparticles were 5-15 nm. The energy dispersive X-ray (EDX) 
      and elemental mapping results indicated the maximum distribution of gold and 
      silver elements in the respective nanoproducts, which further corresponds the 
      purity. Further, the X-ray diffraction (XRD) results confirm the crystalline 
      nature of synthesized nanoparticles. The biosynthesized AgNPs served as an 
      ef fi cient antimicrobial agent at 3 mug concentration against many pathogenic 
      strains for instance, Escherichia coli, Salmonella enterica, Vibrio 
      parahaemolyticus, Staphylococcus aureus, Bacillus anthracis and Bacillus cereus. 
      In addition, AgNPs showed complete inhibition of biofilm formation by S. aureus 
      and Pseudomonas aeruginosa at 4 mug/ml concentration. Moreover, the AuNPs and 
      AgNPs found as a potent anticoagulant agent. Thus, the study claims the rapid 
      synthesis of gold and silver nanoparticles by fresh P. ginseng leaf extract and 
      its biological applications.
FAU - Singh, Priyanka
AU  - Singh P
AD  - a Department of Oriental Medicine Biotechnology , Ginseng Bank, College of Life 
      Science, Kyung Hee University , Seocheon-dong, Giheung-gu , Yongin-si , 
      Gyeonggi-do , Republic of Korea.
FAU - Kim, Yeon Ju
AU  - Kim YJ
AD  - a Department of Oriental Medicine Biotechnology , Ginseng Bank, College of Life 
      Science, Kyung Hee University , Seocheon-dong, Giheung-gu , Yongin-si , 
      Gyeonggi-do , Republic of Korea.
FAU - Yang, Deok Chun
AU  - Yang DC
AD  - a Department of Oriental Medicine Biotechnology , Ginseng Bank, College of Life 
      Science, Kyung Hee University , Seocheon-dong, Giheung-gu , Yongin-si , 
      Gyeonggi-do , Republic of Korea.
AD  - b Graduate School of Biotechnology , College of Life Science, Kyung Hee 
      University , Yongin-si , Gyeonggi-do , Republic of Korea.
LA  - eng
PT  - Journal Article
DEP - 20151224
PL  - England
TA  - Artif Cells Nanomed Biotechnol
JT  - Artificial cells, nanomedicine, and biotechnology
JID - 101594777
RN  - 0 (Anti-Bacterial Agents)
RN  - 3M4G523W1G (Silver)
RN  - 7440-57-5 (Gold)
SB  - IM
MH  - *Anti-Bacterial Agents/chemistry/pharmacology
MH  - Bacteria/*growth & development
MH  - *Gold/chemistry/pharmacology
MH  - Metal Nanoparticles/*chemistry/ultrastructure
MH  - Panax/*chemistry
MH  - Plant Leaves/*chemistry
MH  - *Silver/chemistry/pharmacology
OTO - NOTNLM
OT  - Anticoagulation
OT  - Panax ginseng
OT  - antimicrobial activity
OT  - biofilm inhibition
OT  - gold nanoparticles
OT  - silver nanoparticles
EDAT- 2015/12/25 06:00
MHDA- 2017/01/14 06:00
CRDT- 2015/12/25 06:00
PHST- 2015/12/25 06:00 [pubmed]
PHST- 2017/01/14 06:00 [medline]
PHST- 2015/12/25 06:00 [entrez]
AID - 10.3109/21691401.2015.1115410 [doi]
PST - ppublish
SO  - Artif Cells Nanomed Biotechnol. 2016 Dec;44(8):1949-1957. doi: 
      10.3109/21691401.2015.1115410. Epub 2015 Dec 24.