PMID- 26700492
OWN - NLM
STAT- MEDLINE
DCOM- 20160503
LR  - 20181202
IS  - 1471-499X (Electronic)
IS  - 1471-4914 (Print)
IS  - 1471-4914 (Linking)
VI  - 22
IP  - 1
DP  - 2016 Jan
TI  - Achieving Tolerance with Perforin-Secreting Dendritic Cells.
PG  - 3-4
LID - S1471-4914(15)00226-9 [pii]
LID - 10.1016/j.molmed.2015.11.008 [doi]
AB  - Dendritic cells (DCs) regulate the generation of effector adaptive immunity and 
      enforce peripheral tolerance. In the October 2015 issue of Immunity, 
      Zlotnikov-Klionsky et al. present exciting data describing a population of 
      perforin-expressing CD11c(+)DCs that limit obesity as well as metabolic and 
      autoimmune inflammation in mice.
CI  - Copyright (c) 2015. Published by Elsevier Ltd.
FAU - Takenaka, Maisa C
AU  - Takenaka MC
AD  - Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard 
      Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.
FAU - Quintana, Francisco J
AU  - Quintana FJ
AD  - Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard 
      Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. Electronic 
      address: fquintana@rics.bwh.harvard.edu.
LA  - eng
GR  - R01 AI093903/AI/NIAID NIH HHS/United States
PT  - Comment
PT  - Journal Article
DEP - 20151212
PL  - England
TA  - Trends Mol Med
JT  - Trends in molecular medicine
JID - 100966035
RN  - 0 (Pore Forming Cytotoxic Proteins)
SB  - IM
CON - Immunity. 2015 Oct 20;43(4):776-87. PMID: 26384546
MH  - Animals
MH  - Autoimmunity/*immunology
MH  - CD8-Positive T-Lymphocytes/*immunology
MH  - Dendritic Cells/*immunology
MH  - Female
MH  - Inflammation/*immunology
MH  - Male
MH  - Metabolic Syndrome/*immunology
MH  - Pore Forming Cytotoxic Proteins/*analysis
PMC - PMC4707090
MID - NIHMS746634
EDAT- 2015/12/25 06:00
MHDA- 2016/05/04 06:00
PMCR- 2017/01/01
CRDT- 2015/12/25 06:00
PHST- 2015/11/12 00:00 [received]
PHST- 2015/11/20 00:00 [accepted]
PHST- 2015/12/25 06:00 [entrez]
PHST- 2015/12/25 06:00 [pubmed]
PHST- 2016/05/04 06:00 [medline]
PHST- 2017/01/01 00:00 [pmc-release]
AID - S1471-4914(15)00226-9 [pii]
AID - 10.1016/j.molmed.2015.11.008 [doi]
PST - ppublish
SO  - Trends Mol Med. 2016 Jan;22(1):3-4. doi: 10.1016/j.molmed.2015.11.008. Epub 2015 
      Dec 12.