PMID- 26701171
OWN - NLM
STAT- MEDLINE
DCOM- 20170215
LR  - 20220321
IS  - 1873-622X (Electronic)
IS  - 0005-7967 (Print)
IS  - 0005-7967 (Linking)
VI  - 77
DP  - 2016 Feb
TI  - Mindfulness-Oriented Recovery Enhancement versus CBT for co-occurring substance 
      dependence, traumatic stress, and psychiatric disorders: Proximal outcomes from a 
      pragmatic randomized trial.
PG  - 7-16
LID - S0005-7967(15)30061-9 [pii]
LID - 10.1016/j.brat.2015.11.012 [doi]
AB  - In many clinical settings, there is a high comorbidity between substance use 
      disorders, psychiatric disorders, and traumatic stress. Novel therapies are 
      needed to address these co-occurring issues efficiently. The aim of the present 
      study was to conduct a pragmatic randomized controlled trial comparing 
      Mindfulness-Oriented Recovery Enhancement (MORE) to group Cognitive-Behavioral 
      Therapy (CBT) and treatment-as-usual (TAU) for previously homeless men residing 
      in a therapeutic community. Men with co-occurring substance use and psychiatric 
      disorders, as well as extensive trauma histories, were randomly assigned to 10 
      weeks of group treatment with MORE (n = 64), CBT (n = 64), or TAU (n = 52). Study 
      findings indicated that from pre-to post-treatment MORE was associated with 
      modest yet significantly greater improvements in substance craving, 
      post-traumatic stress, and negative affect than CBT, and greater improvements in 
      post-traumatic stress and positive affect than TAU. A significant indirect effect 
      of MORE on decreasing craving and post-traumatic stress by increasing 
      dispositional mindfulness was observed, suggesting that MORE may target these 
      issues via enhancing mindful awareness in everyday life. This pragmatic trial 
      represents the first head-to-head comparison of MORE against an 
      empirically-supported treatment for co-occurring disorders. Results suggest that 
      MORE, as an integrative therapy designed to bolster self-regulatory capacity, may 
      hold promise as a treatment for intersecting clinical conditions.
CI  - Copyright (c) 2015 Elsevier Ltd. All rights reserved.
FAU - Garland, Eric L
AU  - Garland EL
AD  - University of Utah, USA. Electronic address: eric.garland@socwk.utah.edu.
FAU - Roberts-Lewis, Amelia
AU  - Roberts-Lewis A
AD  - University of North Carolina at Chapel Hill, USA.
FAU - Tronnier, Christine D
AU  - Tronnier CD
AD  - Smith College, USA.
FAU - Graves, Rebecca
AU  - Graves R
AD  - Triangle Residential Options for Substance Abusers, Inc., USA.
FAU - Kelley, Karen
AU  - Kelley K
AD  - Triangle Residential Options for Substance Abusers, Inc., USA.
LA  - eng
GR  - R34 DA037005/DA/NIDA NIH HHS/United States
GR  - R34DA037005/DA/NIDA NIH HHS/United States
GR  - TI 020489/TI/CSAT SAMHSA HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, U.S. Gov't, P.H.S.
DEP - 20151127
PL  - England
TA  - Behav Res Ther
JT  - Behaviour research and therapy
JID - 0372477
SB  - IM
EIN - Behav Res Ther. 2018 Jan;100:78. PMID: 28964403
MH  - Adult
MH  - Awareness
MH  - Cognitive Behavioral Therapy/*methods
MH  - Comorbidity
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mindfulness/*methods
MH  - Psychotherapy, Group
MH  - Stress Disorders, Traumatic/psychology/*therapy
MH  - Substance-Related Disorders/psychology/*therapy
MH  - Treatment Outcome
PMC - PMC4752876
MID - NIHMS745142
OTO - NOTNLM
OT  - Addiction
OT  - Emotion regulation
OT  - Mindfulness
OT  - PTSD
OT  - Reappraisal
OT  - Savoring
OT  - Transdiagnostic
COIS- Conflict of interest: The first author (ELG) developed the Mindfulness-Oriented 
      Recovery Enhancement (MORE) intervention, and has received income from the MORE 
      treatment manual (Garland, 2013) and therapist trainings.
EDAT- 2015/12/25 06:00
MHDA- 2017/02/16 06:00
PMCR- 2017/02/01
CRDT- 2015/12/25 06:00
PHST- 2015/03/03 00:00 [received]
PHST- 2015/11/15 00:00 [revised]
PHST- 2015/11/24 00:00 [accepted]
PHST- 2015/12/25 06:00 [entrez]
PHST- 2015/12/25 06:00 [pubmed]
PHST- 2017/02/16 06:00 [medline]
PHST- 2017/02/01 00:00 [pmc-release]
AID - S0005-7967(15)30061-9 [pii]
AID - 10.1016/j.brat.2015.11.012 [doi]
PST - ppublish
SO  - Behav Res Ther. 2016 Feb;77:7-16. doi: 10.1016/j.brat.2015.11.012. Epub 2015 Nov 
      27.