PMID- 26702663
OWN - NLM
STAT- MEDLINE
DCOM- 20160401
LR  - 20181202
IS  - 1002-0098 (Print)
IS  - 1002-0098 (Linking)
VI  - 50
IP  - 8
DP  - 2015 Aug
TI  - [Development of novel self-healing and antibacterial resin composite containing 
      microcapsules filled with polymerizable healing monomer].
PG  - 469-73
AB  - OBJECTIVE: To develop novel self- healing and antibacterial resin composite 
      containing microcapsules filled with polymerizable healing monomer, and to 
      measure its properties for further clinical application. METHODS: Microcapsules 
      filled with healing monomer of triethylene glycol dimethacrylate were synthesized 
      according to methods introduced in the previous research. Microcapsules were 
      added into novel resin composite containing nano-antibacterial silica fillers 
      grafted with long chain alkyl quaternary ammonium at mass fractions of 0, 2.5%, 
      5.0%, 7.5% or 10.0%. A commercial resin composite (Tetric N-Ceram) was used as 
      control. Flexural test was used to measure resin composite flexural strength and 
      elastic modulus. The single edge V-notched beam method was used to measure 
      fracture toughness and self-healing efficiency. Scanning electron microscope 
      (SEM) was used to examine the fractured surface of selected specimen for 
      investigation of fracture mechanisms. RESULTS: The flexural strength and elastic 
      modulus of the resin composite were (96.4 +/- 14.3) MPa and (6.2 +/- 1.1) GPa 
      respectively after incorporation of microcapsules up to 7.5%, and no significant 
      difference was found between the experimental group and the control group [(99.1 
      +/- 11.9) MPa and (6.1 +/- 1.1) GPa] (P>0.05). The self-healing efficiency of (66.8 +/- 
      7.0)% and (79.3 +/- 9.7)% were achieved for resin composite with microcapsule mass 
      fractions at 7.5% and 10.0%. SEM image showed that irregular films covered the 
      fractured surface. Conclusions This novel self-healing and antibacterial resin 
      composite containing microcapsules filled with polymerizable healing monomer 
      exhibited a promising self- healing ability, which enabled itself well up for 
      combating bulk fracture and secondary caries in clinical application.
FAU - Wu, Junling
AU  - Wu J
AD  - Department of Prosthodontics, School of Stomatology, Shandong University; 
      Shandong Provincial Key Laboratory of Oral Biomedicine, Jinan 250012, China.
FAU - Zhang, Qiang
AU  - Zhang Q
FAU - Zhu, Ting
AU  - Zhu T
FAU - Ge, Jianhua
AU  - Ge J
FAU - Zhou, Chuanjian
AU  - Zhou C
AD  - Research Institute of Polymer Materials, School of Materials Science and 
      Engineering, Shandong University, Jinan 250061, China, Email: 
      zhouchuanjian@sdu.edu.cn.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Kou Qiang Yi Xue Za Zhi
JT  - Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese 
      journal of stomatology
JID - 8711066
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Capsules)
RN  - 0 (Composite Resins)
RN  - 0 (Polymethacrylic Acids)
RN  - 0 (Tetric ceram)
RN  - 14I47YJ5EY (triethylene glycol dimethacrylate)
RN  - 3WJQ0SDW1A (Polyethylene Glycols)
RN  - 454I75YXY0 (Bisphenol A-Glycidyl Methacrylate)
RN  - 7631-86-9 (Silicon Dioxide)
SB  - IM
MH  - *Anti-Bacterial Agents
MH  - Bisphenol A-Glycidyl Methacrylate/*chemical synthesis
MH  - Capsules
MH  - Composite Resins/chemistry
MH  - Drug Compounding/methods
MH  - Elastic Modulus
MH  - Humans
MH  - Microscopy, Electrochemical, Scanning
MH  - Polyethylene Glycols/*chemistry
MH  - Polymerization
MH  - Polymethacrylic Acids/*chemistry
MH  - *Silicon Dioxide
EDAT- 2015/12/26 06:00
MHDA- 2016/04/02 06:00
CRDT- 2015/12/26 06:00
PHST- 2015/12/26 06:00 [entrez]
PHST- 2015/12/26 06:00 [pubmed]
PHST- 2016/04/02 06:00 [medline]
PST - ppublish
SO  - Zhonghua Kou Qiang Yi Xue Za Zhi. 2015 Aug;50(8):469-73.