PMID- 26714699
OWN - NLM
STAT- MEDLINE
DCOM- 20170222
LR  - 20220318
IS  - 1573-2649 (Electronic)
IS  - 0962-9343 (Linking)
VI  - 25
IP  - 6
DP  - 2016 Jun
TI  - Validity, responsiveness, and minimal clinically important difference of EQ-5D-5L 
      in stroke patients undergoing rehabilitation.
PG  - 1585-96
LID - 10.1007/s11136-015-1196-z [doi]
AB  - PURPOSE: To examine the criterion validity, responsiveness, and minimal 
      clinically important difference (MCID) of the EuroQoL 5-Dimensions Questionnaire 
      (EQ-5D-5L) and visual analog scale (EQ-VAS) in people receiving rehabilitation 
      after stroke. METHODS: The EQ-5D-5L, along with four criterion measures-the 
      Medical Research Council scales for muscle strength, the Fugl-Meyer assessment, 
      the functional independence measure, and the Stroke Impact Scale-was administered 
      to 65 patients with stroke before and after 3- to 4-week therapy. Criterion 
      validity was estimated using the Spearman correlation coefficient. Responsiveness 
      was analyzed by the effect size, standardized response mean (SRM), and criterion 
      responsiveness. The MCID was determined by anchor-based and distribution-based 
      approaches. The percentage of patients exceeding the MCID was also reported. 
      RESULTS: Concurrent validity of the EQ-Index was better compared with the EQ-VAS. 
      The EQ-Index has better power for predicting the rehabilitation outcome in the 
      activities of daily living than other motor-related outcome measures. The 
      EQ-Index was moderately responsive to change (SRM = 0.63), whereas the EQ-VAS was 
      only mildly responsive to change. The MCID estimation of the EQ-Index (the 
      percentage of patients exceeding the MCID) was 0.10 (33.8 %) and 0.10 (33.8 %) 
      based on the anchor-based and distribution-based approaches, respectively, and 
      the estimation of EQ-VAS was 8.61 (41.5 %) and 10.82 (32.3 %). CONCLUSIONS: The 
      EQ-Index has shown reasonable concurrent validity, limited predictive validity, 
      and acceptable responsiveness for detecting the health-related quality of life in 
      stroke patients undergoing rehabilitation, but not for EQ-VAS. Future research 
      considering different recovery stages after stroke is warranted to validate these 
      estimations.
FAU - Chen, Poyu
AU  - Chen P
AD  - Department of Occupational Therapy and Graduate Institute of Behavioral Sciences, 
      College of Medicine, Chang Gung University, 259 Wenhua 1st Road, Taoyuan, Taiwan.
FAU - Lin, Keh-Chung
AU  - Lin KC
AD  - School of Occupational Therapy, College of Medicine, National Taiwan University, 
      Taipei, Taiwan.
AD  - Division of Occupational Therapy, Department of Physical Medicine and 
      Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
FAU - Liing, Rong-Jiuan
AU  - Liing RJ
AD  - Department of Occupational Therapy and Graduate Institute of Behavioral Sciences, 
      College of Medicine, Chang Gung University, 259 Wenhua 1st Road, Taoyuan, Taiwan.
FAU - Wu, Ching-Yi
AU  - Wu CY
AD  - Department of Occupational Therapy and Graduate Institute of Behavioral Sciences, 
      College of Medicine, Chang Gung University, 259 Wenhua 1st Road, Taoyuan, Taiwan. 
      cywu@mail.cgu.edu.tw.
AD  - Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan. 
      cywu@mail.cgu.edu.tw.
FAU - Chen, Chia-Ling
AU  - Chen CL
AD  - Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, 
      Taoyuan, Taiwan.
AD  - Graduate Institute of Early Intervention, College of Medicine, Chang Gung 
      University, Taoyuan, Taiwan.
FAU - Chang, Ku-Chou
AU  - Chang KC
AD  - Department of Neurology, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
DEP - 20151130
PL  - Netherlands
TA  - Qual Life Res
JT  - Quality of life research : an international journal of quality of life aspects of 
      treatment, care and rehabilitation
JID - 9210257
SB  - IM
MH  - Activities of Daily Living/*psychology
MH  - Adult
MH  - Aged
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Pain Measurement/methods
MH  - Psychometrics/*instrumentation/methods
MH  - Quality of Life/*psychology
MH  - Reproducibility of Results
MH  - Severity of Illness Index
MH  - Stroke/psychology/therapy
MH  - Stroke Rehabilitation/*psychology
MH  - *Surveys and Questionnaires
MH  - Taiwan
MH  - Treatment Outcome
MH  - Visual Analog Scale
OTO - NOTNLM
OT  - EQ-5D-5L
OT  - MCID
OT  - Quality of life
OT  - Rehabilitation
OT  - Stroke
OT  - Validity
EDAT- 2015/12/31 06:00
MHDA- 2017/02/23 06:00
CRDT- 2015/12/31 06:00
PHST- 2015/11/23 00:00 [accepted]
PHST- 2015/12/31 06:00 [entrez]
PHST- 2015/12/31 06:00 [pubmed]
PHST- 2017/02/23 06:00 [medline]
AID - 10.1007/s11136-015-1196-z [pii]
AID - 10.1007/s11136-015-1196-z [doi]
PST - ppublish
SO  - Qual Life Res. 2016 Jun;25(6):1585-96. doi: 10.1007/s11136-015-1196-z. Epub 2015 
      Nov 30.