PMID- 26717507
OWN - NLM
STAT- MEDLINE
DCOM- 20161024
LR  - 20181202
IS  - 1873-4367 (Electronic)
IS  - 0927-7765 (Linking)
VI  - 139
DP  - 2016 Mar 1
TI  - Construction of microgels embedded robust ultrafiltration membranes for highly 
      effective bioadhesion resistance.
PG  - 199-210
LID - S0927-7765(15)30366-0 [pii]
LID - 10.1016/j.colsurfb.2015.12.018 [doi]
AB  - Effective and robust anti-bioadhesion ultrafiltration membranes were fabricated 
      in this paper via physically blending of anti-bioadhesion microgels. The 
      microgels were synthesized by one-step cross-linking of antifouling segment, 
      poly(ethylene glycol) methacrylate (PEGMA), and electrostatic repulsion segment, 
      methylacrylic acid (MAA). Fourier transform infrared spectroscopy (FTIR) and 
      X-ray photoelectron spectroscopy (XPS) results indicated that large amounts of 
      PEGMA and MAA polymers had been enriched on the membranes surface. Scanning 
      electron microscope (SEM) indicated that the spherical PEGMA-MAA (PM) microgels 
      might form interpenetrating structure with the membrane matrixes, and 
      substantially increased the pore size of the membranes. Water contact angle 
      (WCA), pore size distributions and ultrafiltration tests suggested that the 
      hydrophilicity, porosity, water flux, and antifouling property for the modified 
      membranes were significantly enhanced. More importantly, systematic anti-adhesion 
      investigations of plasma proteins, platelets, bacteria and vein endothelial cells 
      confirmed that the modified membranes owned strong resistance capability to the 
      bioadhesion of various organisms. The results revealed that highly robust and 
      effective anti-bioadhesion ultrafiltration membranes could be prepared via the 
      proposed blending of PM microgels with membrane matrix, thus this approach should 
      be potential in various biomedical or industrial filtration fields where 
      anti-bioadhesion properties were highly demanded.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Xia, Yi
AU  - Xia Y
AD  - College of Polymer Science and Engineering, State Key Laboratory of Polymer 
      Materials Engineering, Sichuan University, Chengdu 610065, China.
FAU - Cheng, Chong
AU  - Cheng C
AD  - College of Polymer Science and Engineering, State Key Laboratory of Polymer 
      Materials Engineering, Sichuan University, Chengdu 610065, China. Electronic 
      address: sagecheng@163.com.
FAU - Wang, Rui
AU  - Wang R
AD  - College of Polymer Science and Engineering, State Key Laboratory of Polymer 
      Materials Engineering, Sichuan University, Chengdu 610065, China.
FAU - He, Chao
AU  - He C
AD  - College of Polymer Science and Engineering, State Key Laboratory of Polymer 
      Materials Engineering, Sichuan University, Chengdu 610065, China.
FAU - Ma, Lang
AU  - Ma L
AD  - College of Polymer Science and Engineering, State Key Laboratory of Polymer 
      Materials Engineering, Sichuan University, Chengdu 610065, China.
FAU - Zhao, Changsheng
AU  - Zhao C
AD  - College of Polymer Science and Engineering, State Key Laboratory of Polymer 
      Materials Engineering, Sichuan University, Chengdu 610065, China; National 
      Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, 
      China. Electronic address: zhaochsh70@163.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20151211
PL  - Netherlands
TA  - Colloids Surf B Biointerfaces
JT  - Colloids and surfaces. B, Biointerfaces
JID - 9315133
RN  - 0 (Acrylates)
RN  - 0 (Gels)
RN  - 0 (Membranes, Artificial)
RN  - 0 (Methacrylates)
RN  - 0 (Polymers)
RN  - 0 (Sulfones)
RN  - 0 (polyethylene glycol methacrylate)
RN  - 059QF0KO0R (Water)
RN  - 25667-42-9 (polyether sulfone)
RN  - 27432CM55Q (Serum Albumin, Bovine)
RN  - 3WJQ0SDW1A (Polyethylene Glycols)
RN  - WC487PR91H (methyl acrylate)
SB  - IM
MH  - Acrylates/*chemistry/pharmacology
MH  - Bacterial Adhesion/drug effects
MH  - Blood Platelets/cytology/drug effects
MH  - Cell Adhesion/drug effects
MH  - Escherichia coli/drug effects/physiology
MH  - Gels
MH  - Human Umbilical Vein Endothelial Cells/cytology/drug effects
MH  - Hydrophobic and Hydrophilic Interactions
MH  - *Membranes, Artificial
MH  - Methacrylates/*chemistry/pharmacology
MH  - Polyethylene Glycols/*chemistry/pharmacology
MH  - Polymers/*chemistry/pharmacology
MH  - Porosity
MH  - Serum Albumin, Bovine/chemistry
MH  - Staphylococcus aureus/drug effects/physiology
MH  - Sulfones/*chemistry/pharmacology
MH  - Ultrafiltration/*instrumentation
MH  - Water/chemistry
OTO - NOTNLM
OT  - Antibacterial
OT  - Antifouling
OT  - Bioadhesion resistance
OT  - PM microgels
OT  - Ultrafiltration membrane
EDAT- 2015/12/31 06:00
MHDA- 2016/10/25 06:00
CRDT- 2015/12/31 06:00
PHST- 2015/09/10 00:00 [received]
PHST- 2015/11/18 00:00 [revised]
PHST- 2015/12/09 00:00 [accepted]
PHST- 2015/12/31 06:00 [entrez]
PHST- 2015/12/31 06:00 [pubmed]
PHST- 2016/10/25 06:00 [medline]
AID - S0927-7765(15)30366-0 [pii]
AID - 10.1016/j.colsurfb.2015.12.018 [doi]
PST - ppublish
SO  - Colloids Surf B Biointerfaces. 2016 Mar 1;139:199-210. doi: 
      10.1016/j.colsurfb.2015.12.018. Epub 2015 Dec 11.