PMID- 26724662
OWN - NLM
STAT- MEDLINE
DCOM- 20160808
LR  - 20181202
IS  - 1872-7727 (Electronic)
IS  - 0720-048X (Linking)
VI  - 85
IP  - 1
DP  - 2016 Jan
TI  - Hybrid Type iterative reconstruction method vs. filter back projection method: 
      Capability for radiation dose reduction and perfusion assessment on dynamic 
      first-pass contrast-enhanced perfusion chest area-detector CT.
PG  - 164-175
LID - S0720-048X(15)30154-6 [pii]
LID - 10.1016/j.ejrad.2015.11.010 [doi]
AB  - PURPOSE: To directly compare the capability of hybrid-type iterative 
      reconstruction (i.e., adaptive iterative dose reduction using 3D processing: AIDR 
      3D) and filter back projection (FBP) for radiation dose reduction during dynamic 
      contrast-enhanced (CE-) perfusion area-detector CT (ADCT) for lung and nodule 
      perfusion assessment. MATERIALS AND METHODS: Thirty-six patients with lung 
      cancers who underwent perfusion ADCT (SD-ADCT) at 120 mA and were enrolled in 
      this study. ADCT data at 80 mA (reduced-dose ADCT: RD-ADCT), 60 mA (low-dose 
      ADCT: LD-ADCT) and 40 mA (very low-dose ADCT: VLD-ADCT) were computationally 
      simulated using SD-ADCT data, and reconstructed with and without AIDR 3D. Image 
      noise and lung and nodule perfusion parameters were evaluated using ROI 
      measurements. To determine the utility of AIDR 3D for dose reduction, image noise 
      was compared between each protocol with and without AIDR 3D by means of the 
      t-test. Correlations and limits of agreement for parameters obtained with SD-ADCT 
      and other protocols were also evaluated. RESULTS: Image noise of all protocols 
      with AIDR 3D was significantly lower than that of LD-ADCT and VLD-ADCT without 
      AIDR 3D (p<0.05). Significant correlations for image noise between SD-ADCT and 
      all protocols with AIDR 3D (0.45 </= r </= 0.99, p<0.0001) were equal to or better 
      than that without AIDR 3D (0.28 </= r </= 0.99, p<0.0001). The limits of agreement 
      for perfusion parameters with AIDR 3D were smaller than those without AIDR 3D for 
      each tube current. CONCLUSION: AIDR 3D is more effective than FBP for dose 
      reduction of perfusion ADCT while maintaining image quality and reducing 
      measurement errors.
CI  - Copyright (c) 2015 Elsevier Ireland Ltd. All rights reserved.
FAU - Ohno, Yoshiharu
AU  - Ohno Y
AD  - Division of Functional and Diagnostic Imaging Research, Department of Radiology, 
      Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; Advanced 
      Biomedical Imaging Research Center, Kobe University Graduate School of Medicine, 
      Kobe, Hyogo, Japan. Electronic address: yosirad@med.kobe-u.ac.jp.
FAU - Koyama, Hisanobu
AU  - Koyama H
AD  - Division of Radiology, Department of Radiology, Kobe University Graduate School 
      of Medicine, Kobe, Hyogo, Japan.
FAU - Fujisawa, Yasuko
AU  - Fujisawa Y
AD  - Toshiba Medical Systems Corporation, Otawara, Tochigi, Japan.
FAU - Yoshikawa, Takeshi
AU  - Yoshikawa T
AD  - Division of Functional and Diagnostic Imaging Research, Department of Radiology, 
      Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; Advanced 
      Biomedical Imaging Research Center, Kobe University Graduate School of Medicine, 
      Kobe, Hyogo, Japan.
FAU - Inokawa, Hiroyasu
AU  - Inokawa H
AD  - Toshiba Medical Systems Corporation, Otawara, Tochigi, Japan.
FAU - Sugihara, Naoki
AU  - Sugihara N
AD  - Toshiba Medical Systems Corporation, Otawara, Tochigi, Japan.
FAU - Seki, Shinichiro
AU  - Seki S
AD  - Division of Radiology, Department of Radiology, Kobe University Graduate School 
      of Medicine, Kobe, Hyogo, Japan.
FAU - Sugimura, Kazuro
AU  - Sugimura K
AD  - Division of Radiology, Department of Radiology, Kobe University Graduate School 
      of Medicine, Kobe, Hyogo, Japan.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20151111
PL  - Ireland
TA  - Eur J Radiol
JT  - European journal of radiology
JID - 8106411
RN  - 0 (Contrast Media)
SB  - IM
MH  - Aged
MH  - Algorithms
MH  - *Contrast Media
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted/*methods
MH  - Imaging, Three-Dimensional
MH  - Lung/diagnostic imaging
MH  - Lung Neoplasms/*diagnostic imaging
MH  - Male
MH  - Prospective Studies
MH  - *Radiation Dosage
MH  - *Radiographic Image Enhancement
MH  - Reproducibility of Results
MH  - Tomography, X-Ray Computed/*methods
OTO - NOTNLM
OT  - CT
OT  - lung
OT  - nodule
OT  - perfusion
OT  - radiation dose
OT  - reconstruction algorithm
EDAT- 2016/01/03 06:00
MHDA- 2016/08/09 06:00
CRDT- 2016/01/03 06:00
PHST- 2015/07/16 00:00 [received]
PHST- 2015/10/23 00:00 [revised]
PHST- 2015/11/04 00:00 [accepted]
PHST- 2016/01/03 06:00 [entrez]
PHST- 2016/01/03 06:00 [pubmed]
PHST- 2016/08/09 06:00 [medline]
AID - S0720-048X(15)30154-6 [pii]
AID - 10.1016/j.ejrad.2015.11.010 [doi]
PST - ppublish
SO  - Eur J Radiol. 2016 Jan;85(1):164-175. doi: 10.1016/j.ejrad.2015.11.010. Epub 2015 
      Nov 11.