PMID- 26725152
OWN - NLM
STAT- MEDLINE
DCOM- 20171018
LR  - 20180627
IS  - 2213-2201 (Electronic)
VI  - 4
IP  - 3
DP  - 2016 May-Jun
TI  - Taxonomy of Allergenic Fungi.
PG  - 375-385.e1
LID - S2213-2198(15)00576-0 [pii]
LID - 10.1016/j.jaip.2015.10.012 [doi]
AB  - The Kingdom Fungi contains diverse eukaryotic organisms including yeasts, molds, 
      mushrooms, bracket fungi, plant rusts, smuts, and puffballs. Fungi have a complex 
      metabolism that differs from animals and plants. They secrete enzymes into their 
      surroundings and absorb the breakdown products of enzyme action. Some of these 
      enzymes are well-known allergens. The phylogenetic relationships among fungi were 
      unclear until recently because classification was based on the sexual state 
      morphology. Fungi lacking an obvious sexual stage were assigned to the 
      artificial, now-obsolete category, "Deuteromycetes" or "Fungi Imperfecti." During 
      the last 20 years, DNA sequencing has resolved 8 fungal phyla, 3 of which contain 
      most genera associated with important aeroallergens: Zygomycota, Ascomycota, and 
      Basidiomycota. Advances in fungal classification have required name changes for 
      some familiar taxa. Because of regulatory constraints, many fungal allergen 
      extracts retain obsolete names. A major benefit from this reorganization is that 
      specific immunoglobulin E (IgE) levels in individuals sensitized to fungi appear 
      to closely match fungal phylogenetic relationships. This close relationship 
      between molecular fungal systematics and IgE sensitization provides an 
      opportunity to systematically look at cross-reactivity and permits 
      representatives from each taxon to serve as a proxy for IgE to the group.
CI  - Copyright (c) 2016 American Academy of Allergy, Asthma & Immunology. Published by 
      Elsevier Inc. All rights reserved.
FAU - Levetin, Estelle
AU  - Levetin E
AD  - Faculty of Biological Science, University of Tulsa, Tulsa, Okla. Electronic 
      address: estelle-levetin@utulsa.edu.
FAU - Horner, W Elliott
AU  - Horner WE
AD  - UL Environment, Marietta, Ga.
FAU - Scott, James A
AU  - Scott JA
AD  - Division of Occupational & Environmental Health, Dalla Lana School of Public 
      Health, University of Toronto, Toronto, Ontario, Canada.
CN  - Environmental Allergens Workgroup
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20151224
PL  - United States
TA  - J Allergy Clin Immunol Pract
JT  - The journal of allergy and clinical immunology. In practice
JID - 101597220
RN  - 0 (Allergens)
SB  - IM
MH  - Allergens/immunology
MH  - Fungi/*classification/immunology
MH  - Humans
OTO - NOTNLM
OT  - Aeroallergens
OT  - Allergy
OT  - Fungi
OT  - Mold
FIR - Barnes, Charles
IR  - Barnes C
FIR - Baxi, Sachin
IR  - Baxi S
FIR - Chew, Ginger L
IR  - Chew GL
FIR - Grimes, Carl
IR  - Grimes C
FIR - Horner, W Elliott
IR  - Horner WE
FIR - Kennedy, Kevin
IR  - Kennedy K
FIR - Larenas-Linnemann, Desiree
IR  - Larenas-Linnemann D
FIR - Levetin, Estelle
IR  - Levetin E
FIR - Miller, J David
IR  - Miller JD
FIR - Phipatanakul, Wanda
IR  - Phipatanakul W
FIR - Portnoy, Jay M
IR  - Portnoy JM
FIR - Scott, James A
IR  - Scott JA
FIR - Williams, P Brock
IR  - Williams PB
EDAT- 2016/01/05 06:00
MHDA- 2017/10/19 06:00
CRDT- 2016/01/04 06:00
PHST- 2015/07/27 00:00 [received]
PHST- 2015/09/19 00:00 [revised]
PHST- 2015/10/16 00:00 [accepted]
PHST- 2016/01/04 06:00 [entrez]
PHST- 2016/01/05 06:00 [pubmed]
PHST- 2017/10/19 06:00 [medline]
AID - S2213-2198(15)00576-0 [pii]
AID - 10.1016/j.jaip.2015.10.012 [doi]
PST - ppublish
SO  - J Allergy Clin Immunol Pract. 2016 May-Jun;4(3):375-385.e1. doi: 
      10.1016/j.jaip.2015.10.012. Epub 2015 Dec 24.