PMID- 26728979 OWN - NLM STAT- MEDLINE DCOM- 20161017 LR - 20231111 IS - 1471-2288 (Electronic) IS - 1471-2288 (Linking) VI - 16 DP - 2016 Jan 5 TI - Creating a literature database of low-calorie sweeteners and health studies: evidence mapping. PG - 1 LID - 10.1186/s12874-015-0105-z [doi] LID - 1 AB - BACKGROUND: Evidence mapping is an emerging tool used to systematically identify, organize and summarize the quantity and focus of scientific evidence on a broad topic, but there are currently no methodological standards. Using the topic of low-calorie sweeteners (LCS) and selected health outcomes, we describe the process of creating an evidence-map database and demonstrate several example descriptive analyses using this database. METHODS: The process of creating an evidence-map database is described in detail. The steps include: developing a comprehensive literature search strategy, establishing study eligibility criteria and a systematic study selection process, extracting data, developing outcome groups with input from expert stakeholders and tabulating data using descriptive analyses. The database was uploaded onto SRDR (Systematic Review Data Repository), an open public data repository. RESULTS: Our final LCS evidence-map database included 225 studies, of which 208 were interventional studies and 17 were cohort studies. An example bubble plot was produced to display the evidence-map data and visualize research gaps according to four parameters: comparison types, population baseline health status, outcome groups, and study sample size. This plot indicated a lack of studies assessing appetite and dietary intake related outcomes using LCS with a sugar intake comparison in people with diabetes. CONCLUSION: Evidence mapping is an important tool for the contextualization of in-depth systematic reviews within broader literature and identifies gaps in the evidence base, which can be used to inform future research. An open evidence-map database has the potential to promote knowledge translation from nutrition science to policy. FAU - Wang, Ding Ding AU - Wang DD AD - Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA. deenawang@gmail.com. FAU - Shams-White, Marissa AU - Shams-White M AD - Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA. Marissa.Shams_White@tufts.edu. FAU - Bright, Oliver John M AU - Bright OJ AD - Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA. oliver-john.bright@tufts.edu. FAU - Parrott, J Scott AU - Parrott JS AD - Department of Interdisciplinary Studies, Rutgers University School of Health Related Professions, Newark, NJ, USA. parrotja@shrp.rutgers.edu. FAU - Chung, Mei AU - Chung M AD - Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA. Mei_Chun.Chung@tufts.edu. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20160105 PL - England TA - BMC Med Res Methodol JT - BMC medical research methodology JID - 100968545 RN - 0 (Non-Nutritive Sweeteners) SB - IM MH - Adult MH - Clinical Trials as Topic MH - Cohort Studies MH - *Databases, Factual MH - Evidence-Based Practice/*methods MH - Female MH - Health Promotion/*statistics & numerical data MH - Humans MH - Infant MH - Non-Nutritive Sweeteners/*administration & dosage MH - Outcome Assessment, Health Care MH - Pregnancy MH - Publications/*statistics & numerical data MH - Reproducibility of Results MH - Review Literature as Topic PMC - PMC4700619 EDAT- 2016/01/06 06:00 MHDA- 2016/10/19 06:00 PMCR- 2016/01/05 CRDT- 2016/01/06 06:00 PHST- 2015/09/03 00:00 [received] PHST- 2015/12/21 00:00 [accepted] PHST- 2016/01/06 06:00 [entrez] PHST- 2016/01/06 06:00 [pubmed] PHST- 2016/10/19 06:00 [medline] PHST- 2016/01/05 00:00 [pmc-release] AID - 10.1186/s12874-015-0105-z [pii] AID - 105 [pii] AID - 10.1186/s12874-015-0105-z [doi] PST - epublish SO - BMC Med Res Methodol. 2016 Jan 5;16:1. doi: 10.1186/s12874-015-0105-z.