PMID- 26731792
OWN - NLM
STAT- MEDLINE
DCOM- 20170427
LR  - 20170427
IS  - 1543-2742 (Electronic)
IS  - 1526-484X (Linking)
VI  - 26
IP  - 4
DP  - 2016 Aug
TI  - Effects of Three Oral Nutritional Supplements on Human Hydration Indices.
PG  - 356-62
LID - 10.1123/ijsnem.2015-0244 [doi]
AB  - Urine color (Ucol) as a hydration assessment tool provides practicality, ease of 
      use, and correlates moderately to strongly with urine specific gravity (Usg) and 
      urine osmolality (Uosm). Indicative of daily fluid turnover, along with solute 
      and urochrome excretion in 24-hr samples, Ucol may also reflect dietary 
      composition. Thus, the purpose of this investigation was to determine the 
      efficacy of Ucol as a hydration status biomarker after nutritional 
      supplementation with beetroot (880 mg), vitamin C (1000 mg), and riboflavin (200 
      mg). Twenty males (Mean +/- SD; age, 21 +/- 2 y; body mass, 82.12 +/- 15.58 kg; height, 
      1.77 +/- 0.06 m) consumed a standardized breakfast and collected all urine voids on 
      one control day (CON) and 1 day after consuming a standardized breakfast and a 
      randomized and double-blinded supplement (SUP) over 3 weeks. Participants 
      replicated exercise and diet for one day before CON, and throughout CON and SUP. 
      Ucol, Usg, Uosm, and urine volume were measured in all 24-hr samples, and Ucol 
      and Usg were measured in all single samples. Ucol was a significant predictor of 
      single sample Usg after all supplements (p < .05). Interestingly, 24-hr Ucol was 
      not a significant predictor of 24-h Usg and Uosm after riboflavin supplementation 
      (p = .20, p = .21). Further, there was a significant difference between CON and 
      SUP 24-h Ucol only after riboflavin supplementation (p < .05). In conclusion, 
      this investigation suggests that users of the UCC (urine color chart) should 
      consider riboflavin supplementation when classifying hydration status and use a 
      combination of urinary biomarkers (e.g., Usg and Ucol), both acutely and over 24 
      hr.
FAU - Ellis, Lindsay A
AU  - Ellis LA
AD  - Centre for Heart, Lung and Vascular Health, School of Health and Exercise 
      Sciences, university of British Columbia, Kelowna, Canada.
FAU - Yates, Brandon A
AU  - Yates BA
FAU - McKenzie, Amy L
AU  - McKenzie AL
FAU - Munoz, Colleen X
AU  - Munoz CX
FAU - Casa, Douglas J
AU  - Casa DJ
FAU - Armstrong, Lawrence E
AU  - Armstrong LE
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20151229
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Biomarkers)
RN  - PQ6CK8PD0R (Ascorbic Acid)
RN  - TLM2976OFR (Riboflavin)
SB  - IM
MH  - Ascorbic Acid/*administration & dosage
MH  - Athletes
MH  - Beta vulgaris/chemistry
MH  - Biomarkers/urine
MH  - Body Mass Index
MH  - Body Weight
MH  - Breakfast
MH  - Diet
MH  - *Dietary Supplements
MH  - Double-Blind Method
MH  - Exercise
MH  - Humans
MH  - Male
MH  - Osmolar Concentration
MH  - Riboflavin/*administration & dosage
MH  - Urinalysis
MH  - *Water-Electrolyte Balance
MH  - Young Adult
EDAT- 2016/01/06 06:00
MHDA- 2017/04/28 06:00
CRDT- 2016/01/06 06:00
PHST- 2016/01/06 06:00 [entrez]
PHST- 2016/01/06 06:00 [pubmed]
PHST- 2017/04/28 06:00 [medline]
AID - 2015-0244 [pii]
AID - 10.1123/ijsnem.2015-0244 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2016 Aug;26(4):356-62. doi: 
      10.1123/ijsnem.2015-0244. Epub 2015 Dec 29.