PMID- 26733764
OWN - NLM
STAT- MEDLINE
DCOM- 20161017
LR  - 20231111
IS  - 1550-2783 (Electronic)
IS  - 1550-2783 (Linking)
VI  - 13
DP  - 2016
TI  - In a single-blind, matched group design: branched-chain amino acid 
      supplementation and resistance training maintains lean body mass during a caloric 
      restricted diet.
PG  - 1
LID - 10.1186/s12970-015-0112-9 [doi]
LID - 1
AB  - BACKGROUND: Athletes and active adults many times have the goal of 
      improving/maintaining fitness while losing weight and this is best achieved by 
      caloric restriction in combination with exercise. However, this poses a risk for 
      lean tissue loss, which can limit performance. Thus, the purpose of this study 
      was to determine the effectiveness of a branched-chain amino acid (BCAA) 
      supplement, in conjunction with heavy resistance training and a carbohydrate 
      caloric-restricted "cut diet" on body composition and muscle fitness. METHODS: 
      Seventeen resistance-trained males (21-28 years of age) were randomized to a BCAA 
      group (n = 9) or a carbohydrate (CHO) group (n = 8) who both received their 
      respective supplement during the 8 weeks of a prescribed body building style 
      resistance training protocol. Subjects were prescribed a hypocaloric diet (based 
      upon pre-intervention analysis) that was to be followed during the study. 
      RESULTS: The BCAA group lost fat mass (-0.05 +/- 0.08 kg;p < .05) and maintained 
      lean mass, while the CHO group lost lean mass (-0.90 +/- 0.06 kg; p < .05) and body 
      mass (-2.3 +/- 0.7 kg; p < .05). Both groups increased 1RM squat, but the increase 
      in the BCAA group (15.1 +/- 2.2 kg; p < .05)was greater (P < 0.05) than the CHO 
      group. The BCAA group increased 1RM bench press (7.1 +/- 1.6 kg; P < 0.05), while 
      the CHO group decreased strength (-3.7 +/- 2.3 kg; P < 0.05). The only change in 
      muscular endurance was an increase in repetitions to fatigue (5.3 +/- 0.2; p < .05) 
      in the CHO group. CONCLUSION: These results show that BCAA supplementation in 
      trained individuals performing resistance training while on a hypocaloric diet 
      can maintain lean mass and preserve skeletal muscle performance while losing fat 
      mass.
FAU - Dudgeon, Wesley David
AU  - Dudgeon WD
AD  - Department of Health and Human Performance, College of Charleston, 24 George 
      Street, Charleston, SC 29424 USA.
FAU - Kelley, Elizabeth Page
AU  - Kelley EP
AD  - Department of Health and Human Performance, College of Charleston, 24 George 
      Street, Charleston, SC 29424 USA.
FAU - Scheett, Timothy Paul
AU  - Scheett TP
AD  - Department of Health and Human Performance, College of Charleston, 24 George 
      Street, Charleston, SC 29424 USA.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20160105
PL  - United States
TA  - J Int Soc Sports Nutr
JT  - Journal of the International Society of Sports Nutrition
JID - 101234168
RN  - 0 (Amino Acids, Branched-Chain)
SB  - IM
MH  - Adult
MH  - Amino Acids, Branched-Chain/*administration & dosage
MH  - *Athletes
MH  - Body Composition
MH  - Body Mass Index
MH  - Caloric Restriction
MH  - Diet Records
MH  - Diet, Carbohydrate-Restricted
MH  - *Dietary Supplements
MH  - Humans
MH  - Male
MH  - Muscle Strength/*drug effects/physiology
MH  - Muscle, Skeletal/*drug effects/physiology
MH  - Patient Compliance/*statistics & numerical data
MH  - Physical Endurance/*drug effects/physiology
MH  - Resistance Training/*methods
MH  - Single-Blind Method
MH  - Sports Nutritional Physiological Phenomena
MH  - Treatment Outcome
PMC - PMC4700774
OTO - NOTNLM
OT  - Cut diet
OT  - Fat mass
OT  - Lean mass
EDAT- 2016/01/07 06:00
MHDA- 2016/10/19 06:00
PMCR- 2016/01/05
CRDT- 2016/01/07 06:00
PHST- 2015/08/20 00:00 [received]
PHST- 2015/12/17 00:00 [accepted]
PHST- 2016/01/07 06:00 [entrez]
PHST- 2016/01/07 06:00 [pubmed]
PHST- 2016/10/19 06:00 [medline]
PHST- 2016/01/05 00:00 [pmc-release]
AID - 112 [pii]
AID - 10.1186/s12970-015-0112-9 [doi]
PST - epublish
SO  - J Int Soc Sports Nutr. 2016 Jan 5;13:1. doi: 10.1186/s12970-015-0112-9. 
      eCollection 2016.