PMID- 26734842
OWN - NLM
STAT- MEDLINE
DCOM- 20161027
LR  - 20170103
IS  - 1526-4602 (Electronic)
IS  - 1525-7797 (Linking)
VI  - 17
IP  - 2
DP  - 2016 Feb 8
TI  - Surface-Functionalization of Nanostructured Cellulose Aerogels by Solid State 
      Eumelanin Coating.
PG  - 564-71
LID - 10.1021/acs.biomac.5b01497 [doi]
AB  - Bioinspired aerogel functionalization by surface modification and coating is in 
      high demand for biomedical and technological applications. In this paper, we 
      report an expedient three-step entry to all-natural surface-functionalized 
      nanostructured aerogels based on (a) TEMPO/NaClO promoted synthesis of cellulose 
      nanofibers (TOCNF); (b) freeze-drying for aerogel preparation; and (c) surface 
      coating with a eumelanin thin film by ammonia-induced solid state polymerization 
      (AISSP) of 5,6-dihydroxyindole (DHI) or 5,6-dihydroxyindole-2-carboxylic acid 
      (DHICA) previously deposited from an organic solution. Scanning electron 
      microscopy showed uniform deposition of the dark eumelanin coating on the 
      template surface without affecting porosity, whereas solid state (13)C NMR and 
      electron paramagnetic resonance (EPR) spectroscopy confirmed the eumelanin-type 
      character of the coatings. DHI melanin coating was found to confer to TOCNF 
      templates a potent antioxidant activity, as tested by the 
      2,2-diphenyl-1-picrylhydrazyl (DPPH) and 
      2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays as well as 
      strong dye adsorption capacity, as tested on methylene blue. The unprecedented 
      combination of nanostructured cellulose and eumelanin thin films disclosed herein 
      implements an original all-natural multifunctional aerogel biomaterial realized 
      via an innovative coating methodology.
FAU - Panzella, Lucia
AU  - Panzella L
AD  - Department of Chemical Sciences, University of Naples "Federico II", Complesso 
      Universitario Monte S.Angelo , via Cintia 4, I-80126 Naples, Italy.
FAU - Melone, Lucio
AU  - Melone L
AD  - Department of Chemistry, Materials, and Chemical Engineering "G. Natta", 
      Politecnico di Milano , Via Mancinelli 7, I-20131 Milano, Italy.
AD  - INSTM, National Consortium of Materials Science and Technology, Local Unit 
      Politecnico di Milano , Piazza Leonardo da Vinci 32, I-20133 Milan, Italy.
AD  - Universita degli studi e-Campus, Via Isimbardi 10, I-22060 Novedrate, Como, 
      Italy.
FAU - Pezzella, Alessandro
AU  - Pezzella A
AD  - Department of Chemical Sciences, University of Naples "Federico II", Complesso 
      Universitario Monte S.Angelo , via Cintia 4, I-80126 Naples, Italy.
FAU - Rossi, Bianca
AU  - Rossi B
AD  - Department of Chemistry, Materials, and Chemical Engineering "G. Natta", 
      Politecnico di Milano , Via Mancinelli 7, I-20131 Milano, Italy.
AD  - INSTM, National Consortium of Materials Science and Technology, Local Unit 
      Politecnico di Milano , Piazza Leonardo da Vinci 32, I-20133 Milan, Italy.
FAU - Pastori, Nadia
AU  - Pastori N
AD  - Department of Chemistry, Materials, and Chemical Engineering "G. Natta", 
      Politecnico di Milano , Via Mancinelli 7, I-20131 Milano, Italy.
AD  - INSTM, National Consortium of Materials Science and Technology, Local Unit 
      Politecnico di Milano , Piazza Leonardo da Vinci 32, I-20133 Milan, Italy.
FAU - Perfetti, Marco
AU  - Perfetti M
AD  - Department of Chemical Sciences, University of Naples "Federico II", Complesso 
      Universitario Monte S.Angelo , via Cintia 4, I-80126 Naples, Italy.
AD  - CSGI (Consorzio per lo Sviluppo dei Sistemi a Grande Interfase), Florence, Italy.
FAU - D'Errico, Gerardino
AU  - D'Errico G
AD  - Department of Chemical Sciences, University of Naples "Federico II", Complesso 
      Universitario Monte S.Angelo , via Cintia 4, I-80126 Naples, Italy.
AD  - CSGI (Consorzio per lo Sviluppo dei Sistemi a Grande Interfase), Florence, Italy.
FAU - Punta, Carlo
AU  - Punta C
AD  - Department of Chemistry, Materials, and Chemical Engineering "G. Natta", 
      Politecnico di Milano , Via Mancinelli 7, I-20131 Milano, Italy.
AD  - INSTM, National Consortium of Materials Science and Technology, Local Unit 
      Politecnico di Milano , Piazza Leonardo da Vinci 32, I-20133 Milan, Italy.
FAU - d'Ischia, Marco
AU  - d'Ischia M
AD  - Department of Chemical Sciences, University of Naples "Federico II", Complesso 
      Universitario Monte S.Angelo , via Cintia 4, I-80126 Naples, Italy.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160119
PL  - United States
TA  - Biomacromolecules
JT  - Biomacromolecules
JID - 100892849
RN  - 0 (Benzothiazoles)
RN  - 0 (Biphenyl Compounds)
RN  - 0 (Free Radical Scavengers)
RN  - 0 (Gels)
RN  - 0 (Melanins)
RN  - 0 (Picrates)
RN  - 0 (Sulfonic Acids)
RN  - 12627-86-0 (eumelanin)
RN  - 28752-68-3 (2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid)
RN  - 9004-34-6 (Cellulose)
RN  - DFD3H4VGDH (1,1-diphenyl-2-picrylhydrazyl)
RN  - T42P99266K (Methylene Blue)
SB  - IM
MH  - Adsorption
MH  - Benzothiazoles/chemistry
MH  - Biphenyl Compounds/chemistry
MH  - Cellulose/*chemistry/ultrastructure
MH  - Free Radical Scavengers/chemistry
MH  - Gels
MH  - Melanins/*chemistry
MH  - Methylene Blue/chemistry
MH  - Nanofibers/*chemistry/ultrastructure
MH  - Picrates/chemistry
MH  - Polymerization
MH  - Porosity
MH  - Sulfonic Acids/chemistry
EDAT- 2016/01/07 06:00
MHDA- 2016/11/01 06:00
CRDT- 2016/01/07 06:00
PHST- 2016/01/07 06:00 [entrez]
PHST- 2016/01/07 06:00 [pubmed]
PHST- 2016/11/01 06:00 [medline]
AID - 10.1021/acs.biomac.5b01497 [doi]
PST - ppublish
SO  - Biomacromolecules. 2016 Feb 8;17(2):564-71. doi: 10.1021/acs.biomac.5b01497. Epub 
      2016 Jan 19.