PMID- 26735547 OWN - NLM STAT- MEDLINE DCOM- 20160512 LR - 20240324 IS - 1536-5964 (Electronic) IS - 0025-7974 (Print) IS - 0025-7974 (Linking) VI - 95 IP - 1 DP - 2016 Jan TI - Regime for Bowel Preparation in Patients Scheduled to Colonoscopy: Low-Residue Diet or Clear Liquid Diet? Evidence From Systematic Review With Power Analysis. PG - e2432 LID - 10.1097/MD.0000000000002432 [doi] LID - e2432 AB - Clear liquid diet (CLD) is used to perform bowel preparation before colonoscopy traditionally, but several clinical studies indicated that low-residue diet (LRD) generates equal effects to CLD and a conclusive conclusion has not yet been yielded. The systematic review was performed to address this conflict and facilitate informed decision-making eventually. To capture randomized controlled trials (RCTs) comparing LRD with CLD in terms of bowel preparation, a search was performed in PubMed, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), Science Direct, recent conference abstracts, Google Scholar, and Clinicaltrials.gov through May 2015. We performed all meta-analyses based on fixed- or random-effects model, which is generated from clinical characteristics and methodology. Moreover, the G*Power software was adopted to achieve statistical power for each outcome. In total, we captured 109 potential citations at initial search stage and 2 topic-related articles were included through other sources. After critical appraisal, 7 RCTs were eligible for our inclusion criteria. Meta-analyses generated similar effects in bowel preparation quality, efficacy of colon cleansing, and compliance with recommended dietary regime when LRD versus CLD regime, but patients who were prescribed to receive LRD have slightly better tolerance (RR, 1.06; 95% CI, 1.02-1.11) and tended to repeat the same preparation regime in future (RR, 1.17; 95% CI, 1.09-1.26) relative to patients in CLD. Importantly, both regimes resulted in similar adverse events (AEs). With the best available evidence, LRD could be recommended to be as standard regime for bowel preparation prior to colonoscopy. FAU - Song, Guo-Min AU - Song GM AD - From the Department of Nursing, Tianjin Hospital, Tianjin, China (G-MS); Graduated College, Tianjin University of Traditional Chinese Medicine, Tianjin, China (XT, LM, L-JY, TS, ZZ); and Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China (XT, ZZ). FAU - Tian, Xu AU - Tian X FAU - Ma, Li AU - Ma L FAU - Yi, Li-Juan AU - Yi LJ FAU - Shuai, Ting AU - Shuai T FAU - Zeng, Zi AU - Zeng Z FAU - Zeng, Xian-Tao AU - Zeng XT LA - eng PT - Journal Article PT - Meta-Analysis PT - Review PT - Systematic Review PL - United States TA - Medicine (Baltimore) JT - Medicine JID - 2985248R SB - IM MH - Colonoscopy/*methods MH - Diet/*methods MH - Humans MH - Patient Compliance MH - Patient Preference MH - Randomized Controlled Trials as Topic PMC - PMC4706267 COIS- The authors have no funding or conflicts of interest to disclose. EDAT- 2016/01/07 06:00 MHDA- 2016/05/14 06:00 PMCR- 2016/01/08 CRDT- 2016/01/07 06:00 PHST- 2016/01/07 06:00 [entrez] PHST- 2016/01/07 06:00 [pubmed] PHST- 2016/05/14 06:00 [medline] PHST- 2016/01/08 00:00 [pmc-release] AID - 00005792-201601050-00030 [pii] AID - 10.1097/MD.0000000000002432 [doi] PST - ppublish SO - Medicine (Baltimore). 2016 Jan;95(1):e2432. doi: 10.1097/MD.0000000000002432.