PMID- 26737210
OWN - NLM
STAT- MEDLINE
DCOM- 20160912
LR  - 20220321
IS  - 2694-0604 (Electronic)
IS  - 2375-7477 (Linking)
VI  - 2015
DP  - 2015
TI  - Lempel-Ziv and multiscale Lempel-Ziv complexity in depression.
PG  - 4158-61
LID - 10.1109/EMBC.2015.7319310 [doi]
AB  - There is a high demand for objective indicators in diagnosis of depression as 
      diagnosis of depression is still based on psychiatrist's subjective judgment. A 
      nonlinear method Lempel Ziv Complexity (LZC) has been previously successfully 
      used for detection of neuronal or mental disorders based on 
      electroencephalographic (EEG) signals. However, the method overlooks the high 
      frequency content of EEG signals. Therefore, this study is aimed to find out 
      whether the use of Multiscale Lempel Ziv Complexity (MLZC), considering also high 
      frequencies, could overcome the limitations of LZC and better differentiate 
      depression. In current study the EEG recordings were carried out on the groups of 
      depressive and healthy subjects of 11 volunteers each. The LZC and MLZC were 
      calculated on resting EEG signals in eyes open condition from 30 channels at a 
      length of 2 minutes. The results revealed the incapability of traditional LZC to 
      differentiate depressive subjects from healthy controls in eyes open condition, 
      while MLZC differentiated two groups in numerous channels at different 
      frequencies, giving the highest classification accuracy in channel F3 (86 %) at 
      frequencies 9 and 15.5 Hz. The results indicate that the high frequency 
      information, which is lost in calculation of traditional LZC, has a great value 
      in differentiating between depressive and control groups.
FAU - Kalev, K
AU  - Kalev K
FAU - Bachmann, M
AU  - Bachmann M
FAU - Orgo, L
AU  - Orgo L
FAU - Lass, J
AU  - Lass J
FAU - Hinrikus, H
AU  - Hinrikus H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Annu Int Conf IEEE Eng Med Biol Soc
JT  - Annual International Conference of the IEEE Engineering in Medicine and Biology 
      Society. IEEE Engineering in Medicine and Biology Society. Annual International 
      Conference
JID - 101763872
SB  - IM
MH  - Adult
MH  - Case-Control Studies
MH  - Depression/*diagnosis/physiopathology
MH  - Electroencephalography/*methods
MH  - Eye
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Signal Processing, Computer-Assisted
EDAT- 2016/01/07 06:00
MHDA- 2016/09/13 06:00
CRDT- 2016/01/07 06:00
PHST- 2016/01/07 06:00 [entrez]
PHST- 2016/01/07 06:00 [pubmed]
PHST- 2016/09/13 06:00 [medline]
AID - 10.1109/EMBC.2015.7319310 [doi]
PST - ppublish
SO  - Annu Int Conf IEEE Eng Med Biol Soc. 2015;2015:4158-61. doi: 
      10.1109/EMBC.2015.7319310.