PMID- 26740774 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1310-2818 (Print) IS - 1314-3530 (Electronic) IS - 1310-2818 (Linking) VI - 28 IP - 4 DP - 2014 Jul 4 TI - Synthesis, characterization and antibacterial assessment of SiO(2)-hydroxypropylmethyl cellulose hybrid materials with embedded silver nanoparticles. PG - 747-752 AB - Antibacterial SiO(2) hybrid materials based on tetraethyl orthosilicate (TEOS), hydroxypropylmethylcellulose (HPMC) and silver were prepared by the sol-gel method. The content of cellulose derivate was 5 wt% and the silver concentration varied from 0.5 wt% to 2.5 wt%. The amorphous nature, morphology and antibacterial behaviour were studied. Fourier transform infrared (FTIR) spectra of the hybrids showed characteristic peaks for SiO(2) network. Scanning electron microscope (SEM) analysis confirmed the formation of spherically shaped silver nanoparticles with a size of 30 nm on the matrix surfaces. Bacillus subtilis and Escherichia coli K12 were used as model microorganisms. The hybrid materials demonstrated bacteriostatic and bactericidal effect on the tested bacteria. Highest sensitivity to the obtained hybrids was observed in B. subtilis with significant lag-phase delay and biggest inhibition zone sizes. FAU - Angelova, Tsvetelina AU - Angelova T AD - Department of Biotechnology, University of Chemical Technology and Metallurgy , Sofia , Bulgaria. FAU - Rangelova, Nadezhda AU - Rangelova N AD - Department of Fundamentals of Chemical Technology, University of Chemical Technology and Metallurgy , Sofia , Bulgaria. FAU - Dineva, Hristina AU - Dineva H AD - Department of Biotechnology, University of Chemical Technology and Metallurgy , Sofia , Bulgaria. FAU - Georgieva, Nelly AU - Georgieva N AD - Department of Biotechnology, University of Chemical Technology and Metallurgy , Sofia , Bulgaria. FAU - Muller, Rudolf AU - Muller R AD - Institute of Technical Biocatalysis, Hamburg University of Technology , Hamburg , Germany. LA - eng PT - Journal Article DEP - 20140923 PL - England TA - Biotechnol Biotechnol Equip JT - Biotechnology, biotechnological equipment JID - 101128940 PMC - PMC4684056 OTO - NOTNLM OT - SiO2 OT - antibacterial activity OT - hydroxypropylmethyl cellulose OT - silver nanoparticles EDAT- 2014/07/04 00:00 MHDA- 2014/07/04 00:01 PMCR- 2015/12/18 CRDT- 2016/01/08 06:00 PHST- 2014/04/24 00:00 [received] PHST- 2014/05/19 00:00 [accepted] PHST- 2016/01/08 06:00 [entrez] PHST- 2014/07/04 00:00 [pubmed] PHST- 2014/07/04 00:01 [medline] PHST- 2015/12/18 00:00 [pmc-release] AID - 944789 [pii] AID - 10.1080/13102818.2014.944789 [doi] PST - ppublish SO - Biotechnol Biotechnol Equip. 2014 Jul 4;28(4):747-752. doi: 10.1080/13102818.2014.944789. Epub 2014 Sep 23.