PMID- 26745830
OWN - NLM
STAT- MEDLINE
DCOM- 20160829
LR  - 20160131
IS  - 1873-5967 (Electronic)
IS  - 1386-6532 (Linking)
VI  - 75
DP  - 2016 Feb
TI  - Fulminant hepatic failure attributed to infection with human herpesvirus 6 
      (HHV-6) in an immunocompetent woman: A case report and review of the literature.
PG  - 27-32
LID - S1386-6532(15)00794-5 [pii]
LID - 10.1016/j.jcv.2015.12.002 [doi]
AB  - Mild disease due to human herpesvirus-6 (HHV-6) has been reported in healthy 
      children. Severe disease due to this virus can occur in immunocompromised 
      patients but is rarely reported in previously healthy adults. We report the case 
      of a previously healthy woman who presented with a skin rash, mild upper 
      respiratory symptoms, and abdominal pain and succumbed to fulminant hepatic 
      failure attributed to infection with HHV-6B. HHV-6 may be more commonly 
      associated with fulminant hepatitis in immunocompetent patients than previously 
      thought and should be considered in the differential diagnosis of patients 
      presenting with skin rash, upper respiratory symptoms, and unexplained hepatitis.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Charnot-Katsikas, Angella
AU  - Charnot-Katsikas A
AD  - Department of Pathology, The University of Chicago Medicine, 5841 S. Maryland 
      Ave., TW003-d, Chicago, IL 60637, USA. Electronic address: 
      Angella.Charnot-Katsikas@uchospitals.edu.
FAU - Baewer, David
AU  - Baewer D
AD  - Coppe Healthcare Solutions, W229 N1870 Westwood Dr., Waukesha, WI 53186, USA. 
      Electronic address: dbaewer@coppehealth.com.
FAU - Cook, Linda
AU  - Cook L
AD  - Department of Laboratory Medicine, University of Washington Medical Center, Box 
      357110 1959 NE Pacific Street, NW120, Seattle, WA 98195-7110, USA. Electronic 
      address: lincook@u.washington.edu.
FAU - David, Michael Z
AU  - David MZ
AD  - Department of Medicine, The University of Chicago Medicine, 5841 S. Maryland 
      Ave., Chicago, IL 60637, USA. Electronic address: 
      mdavid@medicine.bsd.uchicago.edu.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20151214
PL  - Netherlands
TA  - J Clin Virol
JT  - Journal of clinical virology : the official publication of the Pan American 
      Society for Clinical Virology
JID - 9815671
SB  - IM
MH  - Adult
MH  - Diagnosis, Differential
MH  - Female
MH  - Hepatitis/complications/diagnosis
MH  - *Herpesvirus 6, Human
MH  - Humans
MH  - Immunocompromised Host
MH  - Liver Failure, Acute/*etiology
MH  - Roseolovirus Infections/*complications/diagnosis/physiopathology/virology
OTO - NOTNLM
OT  - Fulminant hepatitis
OT  - HHV-6
OT  - Human herpesvirus-6
OT  - Immunocompetent
OT  - Liver failure
OT  - Rash
EDAT- 2016/01/09 06:00
MHDA- 2016/08/30 06:00
CRDT- 2016/01/09 06:00
PHST- 2015/08/21 00:00 [received]
PHST- 2015/11/13 00:00 [revised]
PHST- 2015/12/10 00:00 [accepted]
PHST- 2016/01/09 06:00 [entrez]
PHST- 2016/01/09 06:00 [pubmed]
PHST- 2016/08/30 06:00 [medline]
AID - S1386-6532(15)00794-5 [pii]
AID - 10.1016/j.jcv.2015.12.002 [doi]
PST - ppublish
SO  - J Clin Virol. 2016 Feb;75:27-32. doi: 10.1016/j.jcv.2015.12.002. Epub 2015 Dec 
      14.