PMID- 26749854
OWN - NLM
STAT- MEDLINE
DCOM- 20160122
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 33
IP  - 8
DP  - 2015 Aug
TI  - [Simultaneous determination of fifteen ultraviolet filters in sunscreen cosmetics 
      by high performance liquid chromatography].
PG  - 799-804
AB  - An analytical method for the simultaneous determination of fifteen ultraviolet 
      (UV) filters in sunscreen cosmetics was developed by high performance liquid 
      chromatography (HPLC). Various cosmetic samples including lotions, emulsions, 
      creams and waxes were firstly mixed thoroughly by adding tetrahydrofuran 
      containing 2 g/L ammonium hydroxide followed by vortex and oscillation. If the 
      wax samples were still homogenized incompletely, a ultrasonic oscillation 
      protocol with heating to 50  degrees C was adopted. The homogeneous samples were then 
      ultrasonically extracted by 80% aqueous methanol solution. After centrifugation 
      and micropore filtration, the extracted components were separated on an XTerra MS 
      C18 column with gradient elution by water containing 0. 1% (v/v) formic acid and 
      methanol containing 0. 1% (v/v) formic acid, determined by a diode array detector 
      (DAD) at 280 nm and 311 nm, and quantified using external standard method. 
      Optimization for the pretreatment conditions of different matrices of cosmetics 
      including sample dispersion solvents, extraction solvents and time were carried 
      out. This developed method showed good linearity (r2 >/= 0.999 1) and the limits of 
      quantification (LOQs) were between 1.2 and 5.1 microg/g. The recoveries of the 
      fifteen compounds ranged from 84.2% to 100.7% at three spiked levels with the 
      relative standard deviations (RSDs) between 0.9% and 9.5%. The analytes were well 
      separated and this analytical method proved to be sensitive and accurate, so it 
      can be used in the practical determination of the fifteen UV filters in 
      commercial sunscreen cosmetics.
FAU - Meng, Xianshuang
AU  - Meng X
FAU - Ma, Qiang
AU  - Ma Q
FAU - Bai, Hua
AU  - Bai H
FAU - Zhang, Qing
AU  - Zhang Q
FAU - Lu, Qing
AU  - Lu Q
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Sunscreening Agents)
SB  - IM
MH  - *Chromatography, High Pressure Liquid
MH  - Sunscreening Agents/*analysis
MH  - Ultraviolet Rays
EDAT- 2016/01/12 06:00
MHDA- 2016/01/23 06:00
CRDT- 2016/01/12 06:00
PHST- 2016/01/12 06:00 [entrez]
PHST- 2016/01/12 06:00 [pubmed]
PHST- 2016/01/23 06:00 [medline]
AID - 10.3724/sp.j.1123.2015.03024 [doi]
PST - ppublish
SO  - Se Pu. 2015 Aug;33(8):799-804. doi: 10.3724/sp.j.1123.2015.03024.