PMID- 26755926 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160112 LR - 20201001 IS - 1975-4612 (Print) IS - 2005-9655 (Electronic) IS - 1975-4612 (Linking) VI - 23 IP - 4 DP - 2015 Dec TI - Reassessing the Usefulness of Coronary Artery Calcium Score among Varying Racial and Ethnic Groups by Geographic Locations: Relevance of the Korea Initiatives on Coronary Artery Calcification Registry. PG - 195-203 LID - 10.4250/jcu.2015.23.4.195 [doi] AB - There is some disparity in the morbidity and mortality rates of cardiovascular disease (CVD) according to race, ethnicity, and geographic regions. Although prediction algorithms that evaluate risk of cardiovascular events have been established using traditional risk factors, they have also demonstrated a number of differences along with race and ethnicity. Of various risk assessment modalities, coronary artery calcium (CAC) score is a sensitive marker of calcific atherosclerosis and correlates well with atherosclerotic plaque burden. Although CAC score is now utilized as a useful tool for early detection of coronary artery disease, prior studies have suggested some variability in the presence and severity of coronary calcification according to race, ethnicity, and/or geographic regions. Among Asian populations, it would appear necessary to reappraise the utility of CAC score and whether it remains superior over and above established clinical risk prediction algorithms. To this end, the Korea initiatives on coronary artery calcification (KOICA) registry has been designed to identify the effectiveness of CAC score for primary prevention of CVD in asymptomatic Korean adults. This review discusses the important role of CAC score for prognostication, while also describing the design and rationale of the KOICA registry. FAU - Lee, Ji Hyun AU - Lee JH AD - Division of Cardiology, Yonsei Cardiovascular Center, Yonsei University Health System, Seoul, Korea.; Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital and the Weill Cornell Medical College, New York, NY, USA. FAU - O Hartaigh, Briain AU - O Hartaigh B AD - Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital and the Weill Cornell Medical College, New York, NY, USA. FAU - Han, Donghee AU - Han D AD - Division of Cardiology, Yonsei Cardiovascular Center, Yonsei University Health System, Seoul, Korea.; Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital and the Weill Cornell Medical College, New York, NY, USA. FAU - Park, Hyo Eun AU - Park HE AD - Division of Cardiology, Department of Internal Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea. FAU - Choi, Su-Yeon AU - Choi SY AD - Division of Cardiology, Department of Internal Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea. FAU - Sung, Jidong AU - Sung J AD - Division of Cardiology, Heart Stroke & Vascular Institute, Samsung Medical Center, Seoul, Korea. FAU - Chang, Hyuk-Jae AU - Chang HJ AD - Division of Cardiology, Yonsei Cardiovascular Center, Yonsei University Health System, Seoul, Korea. LA - eng PT - Journal Article PT - Review DEP - 20151230 PL - Korea (South) TA - J Cardiovasc Ultrasound JT - Journal of cardiovascular ultrasound JID - 101477138 PMC - PMC4707303 OTO - NOTNLM OT - Cardiovascular disease OT - Coronary artery calcium score OT - Coronary artery disease OT - Ethnicity OT - Risk prediction algorithm EDAT- 2016/01/13 06:00 MHDA- 2016/01/13 06:01 PMCR- 2015/12/01 CRDT- 2016/01/13 06:00 PHST- 2015/10/01 00:00 [received] PHST- 2015/11/24 00:00 [revised] PHST- 2015/11/25 00:00 [accepted] PHST- 2016/01/13 06:00 [entrez] PHST- 2016/01/13 06:00 [pubmed] PHST- 2016/01/13 06:01 [medline] PHST- 2015/12/01 00:00 [pmc-release] AID - 10.4250/jcu.2015.23.4.195 [doi] PST - ppublish SO - J Cardiovasc Ultrasound. 2015 Dec;23(4):195-203. doi: 10.4250/jcu.2015.23.4.195. Epub 2015 Dec 30.