PMID- 26761077
OWN - NLM
STAT- MEDLINE
DCOM- 20161006
LR  - 20161230
IS  - 1520-5118 (Electronic)
IS  - 0021-8561 (Linking)
VI  - 64
IP  - 5
DP  - 2016 Feb 10
TI  - Non-dioxin-like Polychlorinated Biphenyls (PCBs) and Chlordecone Release from 
      Adipose Tissue to Blood in Response to Body Fat Mobilization in Ewe (Ovis aries).
PG  - 1212-20
LID - 10.1021/acs.jafc.5b05817 [doi]
AB  - Understanding how persistent organic pollutants (POPs) are released from adipose 
      tissue (AT) to blood is a critical step in proposing rearing strategies hastening 
      the removal of POPs from contaminated livestock. The current study aimed to 
      determine in nonlactating ewes whether polychlorinated biphenyls (PCBs) and 
      chlordecone are released from AT to blood along with lipids during body fat 
      mobilization achieved through beta-agonist challenges or undernutrition. beta-Agonist 
      challenges did not affect serum POP concentrations, whereas serum PCBs 138, 153, 
      and 180 were readily increased in response to undernutrition. After 21 days of 
      depuration in undernutrition, AT PCB 153 and 180 concentrations were increased 
      concomitantly with a decrease in adipocyte volume, whereas AT chlordecone 
      concentration was not different from that observed at the end of the well-fed 
      contamination period. Thus, undernutrition may be of practical relevance for 
      accelerating POP depuration unless it is combined with a strategy increasing 
      their excretion pool.
FAU - Lerch, Sylvain
AU  - Lerch S
AD  - Universite de Lorraine, EA 3998, INRA, USC 340, UR Animal et Fonctionnalites des 
      Produits Animaux, TSA 40602 , F-54518 Vandoeuvre-les-Nancy, France.
FAU - Guidou, Come
AU  - Guidou C
AD  - Universite de Lorraine, EA 3998, INRA, USC 340, UR Animal et Fonctionnalites des 
      Produits Animaux, TSA 40602 , F-54518 Vandoeuvre-les-Nancy, France.
FAU - Thome, Jean-Pierre
AU  - Thome JP
AD  - Laboratoire d'Ecologie Animale et d'Ecotoxicologie, Center for Analytical and 
      Research Technology, Universite de Liege , B-4000 Sart-Tilman, Liege, Belgium.
FAU - Jurjanz, Stefan
AU  - Jurjanz S
AD  - Universite de Lorraine, EA 3998, INRA, USC 340, UR Animal et Fonctionnalites des 
      Produits Animaux, TSA 40602 , F-54518 Vandoeuvre-les-Nancy, France.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160128
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Environmental Pollutants)
RN  - 0 (Fats)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
RN  - RG5XJ88UDF (Chlordecone)
SB  - IM
MH  - Adipose Tissue/*metabolism
MH  - Animals
MH  - Chlordecone/blood/*metabolism
MH  - Environmental Pollutants/blood/*metabolism
MH  - Fats/*metabolism
MH  - Polychlorinated Biphenyls/blood/*metabolism
MH  - Sheep/blood/*metabolism
OTO - NOTNLM
OT  - body fat mobilization
OT  - chlordecone
OT  - ewe
OT  - non-dioxin-like polychlorinated biphenyls
OT  - undernutrition
OT  - beta-agonist
EDAT- 2016/01/14 06:00
MHDA- 2016/10/08 06:00
CRDT- 2016/01/14 06:00
PHST- 2016/01/14 06:00 [entrez]
PHST- 2016/01/14 06:00 [pubmed]
PHST- 2016/10/08 06:00 [medline]
AID - 10.1021/acs.jafc.5b05817 [doi]
PST - ppublish
SO  - J Agric Food Chem. 2016 Feb 10;64(5):1212-20. doi: 10.1021/acs.jafc.5b05817. Epub 
      2016 Jan 28.