PMID- 26787362
OWN - NLM
STAT- MEDLINE
DCOM- 20160927
LR  - 20181202
IS  - 1744-7593 (Electronic)
IS  - 1742-5247 (Linking)
VI  - 13
IP  - 5
DP  - 2016
TI  - Facile electrospinning of an efficient drug delivery system.
PG  - 741-53
LID - 10.1517/17425247.2016.1142525 [doi]
AB  - INTRODUCTION: Electrospinning is a facile method for fabricating fibers with 
      diameters in the order of several nanometers to a few micrometers. This 
      technology has great potential for preparing drug delivery systems (DDSs) and has 
      received a great deal of attention in recent years. When combined with certain 
      nanocarriers, such as micelles, nanoparticles or vesicles, an electrospun fiber 
      membrane becomes an efficient and helpful platform for the above-mentioned 
      formulations to achieve sustained and targeted drug release. AREAS COVERED: The 
      developmental process of electrospinning technology is briefly summarized and the 
      drugs and the materials electrospun into drug delivery systems are listed . The 
      application of electrospinning technology in the biomedical field and its current 
      progress are emphasized. EXPERT OPINION: A safe, efficient and multifunctional 
      electrospinning drug delivery system is urgently needed, which requires further 
      studies. Cross-disciplinary strategies that cover pharmaceutical science, 
      material science and computer science may provide guidance in bringing 
      electrospinning technology in drug delivery to fruition.
FAU - Mei, Lan
AU  - Mei L
AD  - a State Key Laboratory of Biotherapy and Cancer Center, and Department of 
      Neurosurgery , West China Hospital, Sichuan University, and Collaborative 
      Innovation Center for Biotherapy , Chengdu , P. R. China.
FAU - Wang, Yuelong
AU  - Wang Y
AD  - a State Key Laboratory of Biotherapy and Cancer Center, and Department of 
      Neurosurgery , West China Hospital, Sichuan University, and Collaborative 
      Innovation Center for Biotherapy , Chengdu , P. R. China.
FAU - Tong, Aiping
AU  - Tong A
AD  - a State Key Laboratory of Biotherapy and Cancer Center, and Department of 
      Neurosurgery , West China Hospital, Sichuan University, and Collaborative 
      Innovation Center for Biotherapy , Chengdu , P. R. China.
FAU - Guo, Gang
AU  - Guo G
AD  - a State Key Laboratory of Biotherapy and Cancer Center, and Department of 
      Neurosurgery , West China Hospital, Sichuan University, and Collaborative 
      Innovation Center for Biotherapy , Chengdu , P. R. China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20160225
PL  - England
TA  - Expert Opin Drug Deliv
JT  - Expert opinion on drug delivery
JID - 101228421
RN  - 0 (Pharmaceutical Preparations)
SB  - IM
MH  - *Chemistry, Pharmaceutical
MH  - Drug Delivery Systems/*methods
MH  - Nanoparticles
MH  - Pharmaceutical Preparations/*administration & dosage
MH  - *Technology, Pharmaceutical
OTO - NOTNLM
OT  - drug delivery system
OT  - electrospinning
OT  - multilevel structure
OT  - nanofiber
EDAT- 2016/01/21 06:00
MHDA- 2016/09/28 06:00
CRDT- 2016/01/21 06:00
PHST- 2016/01/21 06:00 [entrez]
PHST- 2016/01/21 06:00 [pubmed]
PHST- 2016/09/28 06:00 [medline]
AID - 10.1517/17425247.2016.1142525 [doi]
PST - ppublish
SO  - Expert Opin Drug Deliv. 2016;13(5):741-53. doi: 10.1517/17425247.2016.1142525. 
      Epub 2016 Feb 25.