PMID- 26792308 OWN - NLM STAT- MEDLINE DCOM- 20160324 LR - 20181023 IS - 0256-9574 (Print) VI - 106 IP - 1 DP - 2015 Dec 16 TI - Targeting composite treatment of type 2 diabetes in middle-income countries--walking a tightrope between hyperglycaemia and the dangers of hypoglycaemia. PG - 57-61 LID - 10.7196/SAMJ.2016.v106i1.10284 [doi] AB - Middle-income countries need a rational and cost-effective approach to optimise management of type 2 diabetes mellitus (T2DM). There is a paucity of data from such countries on the extent of hypoglycaemia and its consequences for their healthcare systems. This review provides the context for health policy change and evaluates available data on diabetes complications, focusing on hypoglycaemia in T2DM patients in non-Western countries. Suitable guidelines are suggested for these communities, which are in transition from poverty to affluence and in transition from an environment where infectious diseases predominate to one where non-communicable diseases are predominant. FAU - Wing, Jeffrey AU - Wing J AD - Division of Endocrinology, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Donald Gordon Medical Centre, Johannesburg, South Africa. jeffrey.wing@wits.ac.za. FAU - Jivan, Daksha AU - Jivan D LA - eng PT - Journal Article PT - Review DEP - 20151216 PL - South Africa TA - S Afr Med J JT - South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde JID - 0404520 SB - IM EIN - S Afr Med J. 2016 Jun 15;106(8):11183. PMID: 27499415 MH - *Cost of Illness MH - Cost-Benefit Analysis MH - Delivery of Health Care/*economics MH - Developing Countries MH - Diabetes Mellitus, Type 2/*therapy MH - Health Policy/*economics MH - Humans MH - Hyperglycemia/epidemiology/*prevention & control MH - Hypoglycemia/epidemiology/*prevention & control MH - *Income MH - Risk Factors EDAT- 2016/01/23 06:00 MHDA- 2016/03/25 06:00 CRDT- 2016/01/22 06:00 PHST- 2015/11/04 00:00 [received] PHST- 2016/01/22 06:00 [entrez] PHST- 2016/01/23 06:00 [pubmed] PHST- 2016/03/25 06:00 [medline] AID - 10.7196/SAMJ.2016.v106i1.10284 [doi] PST - epublish SO - S Afr Med J. 2015 Dec 16;106(1):57-61. doi: 10.7196/SAMJ.2016.v106i1.10284.