PMID- 26817007 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160128 LR - 20201001 IS - 2287-1012 (Print) IS - 2287-1292 (Electronic) IS - 2287-1012 (Linking) VI - 20 IP - 4 DP - 2015 Dec TI - Incidence trends and associated factors of diabetes mellitus in Korean children and adolescents: a retrospective cohort study in Busan and Gyeongnam. PG - 206-12 LID - 10.6065/apem.2015.20.4.206 [doi] AB - PURPOSE: This study investigated the incidence trends and associated factors of type 1 (T1DM) and type 2 diabetes mellitus (T2DM) in children and adolescents under 15 years of age in Busan and Gyeongnam, Korea from 2001 to 2010. METHODS: Medical records of newly diagnosed diabetes patients (n=328; 160 males, 168 females) were collected in questionnaire form from 5 tertiary and 42 general hospitals in Busan and Gyeongnam. RESULTS: The average crude incidence rate of T1DM and T2DM was 2.01/100,000 (95% confidence interval [CI], 1.76-2.28) and 0.75/100,000 (95% CI, 0.60-0.92), respectively. The incidence rate ratio (IRR) of T1DM was 1.31 (95% CI, 1.01-1.69), and that of T2DM was 1.97 (95% CI, 1.25-3.11) in the latter half-decade (2006 to 2010) compared to the early half-decade (2001 to 2005). There were gradually increasing incidence trends in both T1DM and T2DM over the 10-year period (P for trend: T1DM, 0.0009; T2DM, <0.0001). Age-specific IRR was highest in the 10- to 14-year-old group, regardless of diabetes type. In particular, a rapid increase in incidence of T2DM occurred in the 10- to 14-year-old group. IRR for females was 1.07 (95% CI, 0.83-1.38) for T1DM and 1.56 (95% CI, 1.01-2.41) for T2DM. IRR for Busan (urban) was 1.41 (95% CI, 1.09-1.83) for T1DM and 1.49 (95% CI, 0.96-2.30) for T2DM. CONCLUSION: T1DM and T2DM incidence both increased over time in youth under age 15 living in Busan and Gyeongnam; in particular, the incidence of T2DM in adolescents increased more rapidly. FAU - Lee, Jung Hyun AU - Lee JH AD - Department of Pediatrics, Kosin University Gospel Hospital, Kosin University College of Medicine, Busan, Korea. FAU - Kim, Yu-Mi AU - Kim YM AD - Department of Preventive Medicine, Dong-A University College of Medicine, Busan, Korea. FAU - Kwak, Min Jung AU - Kwak MJ AD - Department of Pediatrics, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea. FAU - Kim, Su Yung AU - Kim SY AD - Department of Pediatrics, Pusan National University Children's Hospital, Pusan National University School of Medicine, Yangsan, Korea. FAU - Kim, Hyun-Ji AU - Kim HJ AD - Department of Pediatrics, Wallace Memorial Baptist Hospital, Busan, Korea. FAU - Cheon, Chong Kun AU - Cheon CK AD - Department of Pediatrics, Pusan National University Children's Hospital, Pusan National University School of Medicine, Yangsan, Korea. FAU - Chung, Woo Yeong AU - Chung WY AD - Department of Pediatrics, Inje University College of Medicine, Busan, Korea. FAU - Choi, Im-Jeong AU - Choi IJ AD - Department of Pediatrics, Mirae Children's Hospital, Busan, Korea. FAU - Hong, Su Young AU - Hong SY AD - Department of Pediatrics, Ijoeun Children's Hospital, Busan, Korea. FAU - Chueh, Hee Won AU - Chueh HW AD - Department of Pediatrics, Dong-A University College of Medicine, Busan, Korea. FAU - Yoo, Jae-Ho AU - Yoo JH AD - Department of Pediatrics, Dong-A University College of Medicine, Busan, Korea. LA - eng PT - Journal Article DEP - 20151231 PL - Korea (South) TA - Ann Pediatr Endocrinol Metab JT - Annals of pediatric endocrinology & metabolism JID - 101588279 PMC - PMC4722160 OTO - NOTNLM OT - Adolescent OT - Child OT - Diabetes OT - Incidence OT - Korea COIS- Conflict of interest: No potential conflict of interest relevant to this article was reported. EDAT- 2016/01/28 06:00 MHDA- 2016/01/28 06:01 PMCR- 2015/12/01 CRDT- 2016/01/28 06:00 PHST- 2015/10/28 00:00 [received] PHST- 2015/12/07 00:00 [revised] PHST- 2015/12/14 00:00 [accepted] PHST- 2016/01/28 06:00 [entrez] PHST- 2016/01/28 06:00 [pubmed] PHST- 2016/01/28 06:01 [medline] PHST- 2015/12/01 00:00 [pmc-release] AID - 10.6065/apem.2015.20.4.206 [doi] PST - ppublish SO - Ann Pediatr Endocrinol Metab. 2015 Dec;20(4):206-12. doi: 10.6065/apem.2015.20.4.206. Epub 2015 Dec 31.