PMID- 26817232
OWN - NLM
STAT- MEDLINE
DCOM- 20160223
LR  - 20181202
IS  - 0125-2208 (Print)
IS  - 0125-2208 (Linking)
VI  - 99 Suppl 1
DP  - 2016 Jan
TI  - Antibacterial Activity of Excretions-Secretions from Chrysomya megacephala 
      Against Escherichia coli.
PG  - S7-11
AB  - BACKGROUND: The blowfly, Chrysomya megacephala, is distributed worldwide. 
      Previous studies found maggot excretions-secretions from other blowfly species 
      inhibited pro-inflammatory response and antimicrobial activity. OBJECTIVE: This 
      study aimed to test the bactericidal activity of excretions-secretions from C. 
      megacephala larvae. MATERIAL AND METHOD: A total of 1,500 3-day-old larvae were 
      used to collect excretions-secretions (ES) modified by the Barnes method. The 
      bactericidal activity ofthe excretions-secretions was test by Pseudomonas 
      aeruginosa, Staphylococcus aureus, and Escherichia coli using suitable liquid 
      culture assay. Scanning electron microscope (SEM) was used to investigate the 
      morphological change ofthe bacteria. RESULTS: E. coli were significantly 
      inhibited by excretions-secretions from C. megacephala larvae. P. aeruginosa and 
      S. aureus were not found to inhibit growth. CONCLUSION: The excretions-secretions 
      from C. megacephala larvae may have a medical property for the inhibition of 
      bacterial growth.
FAU - Chaiwong, Tarinee
AU  - Chaiwong T
FAU - Srivoramas, Thunyakarn
AU  - Srivoramas T
FAU - Sebsumran, Plalakorn
AU  - Sebsumran P
FAU - Panya, Marutpong
AU  - Panya M
FAU - Wanram, Surasak
AU  - Wanram S
FAU - Panomket, Pawana
AU  - Panomket P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Thailand
TA  - J Med Assoc Thai
JT  - Journal of the Medical Association of Thailand = Chotmaihet thangphaet
JID - 7507216
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Animals
MH  - Anti-Bacterial Agents/*pharmacology
MH  - Diptera/*chemistry/growth & development
MH  - Escherichia coli/*drug effects
MH  - Larva/chemistry
MH  - Pseudomonas aeruginosa/*drug effects
MH  - Staphylococcus aureus/*drug effects
EDAT- 2016/01/29 06:00
MHDA- 2016/02/26 06:00
CRDT- 2016/01/29 06:00
PHST- 2016/01/29 06:00 [entrez]
PHST- 2016/01/29 06:00 [pubmed]
PHST- 2016/02/26 06:00 [medline]
PST - ppublish
SO  - J Med Assoc Thai. 2016 Jan;99 Suppl 1:S7-11.