PMID- 26818163
OWN - NLM
STAT- MEDLINE
DCOM- 20160715
LR  - 20221213
IS  - 1319-6138 (Print)
IS  - 1319-6138 (Electronic)
IS  - 1319-6138 (Linking)
VI  - 21
IP  - 1
DP  - 2016 Jan
TI  - Electrophysiological assessment in patients with long term hypoxia.
PG  - 26-9
LID - 10.17712/nsj.2016.1.20150333 [doi]
AB  - OBJECTIVE: To evaluate visual evoked potentials (VEP) patterns in chronic 
      obstructive pulmonary disease (COPD) patients who were compliant with 
      supplemental oxygen treatment relative to non-compliant COPD patients. METHODS: 
      This prospective study protocol was reviewed and approved by the local ethical 
      committee of Selcuk University and the research was performed in the Department 
      of Neurology, Elbistan State Hospital, Kahramanmaras, Turkey from May to October 
      2014. Blood gas measurements and pulmonary function tests were carried out in 
      patients with advanced stage COPD. The VEP was assessed in both eyes in both 
      compliant and non-compliant patients. RESULTS: The study included 43 patients; 24 
      (55.8%) of the patients were not in compliance with their supplemental oxygen 
      treatment, while 19 patients (44.2%) received adequate oxygen treatment. There 
      was no statistically significant difference between patients with regards to 
      pulmonary function test results and blood gas measurements. The VEP latency was 
      significantly greater in both eyes of the non-compliant patients. CONCLUSION: 
      Previous studies have reported prolonged VEP latencies in inflammatory diseases 
      of the central nervous system. Similar electrophysiological findings were 
      observed in our study and we propose that this may be due to oxidative stress, 
      and inflammation that occurs secondary to chronic ischemia.
FAU - Ilik, Faik
AU  - Ilik F
AD  - Department of Neurology, Baskent University, Konya, Turkey. E-mail: 
      faikilik@hotmail.com.
FAU - Pazarli, Ahmet C
AU  - Pazarli AC
FAU - Kayhan, Fatih
AU  - Kayhan F
FAU - Karamanli, Harun
AU  - Karamanli H
FAU - Ozlece, Hatice K
AU  - Ozlece HK
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Saudi Arabia
TA  - Neurosciences (Riyadh)
JT  - Neurosciences (Riyadh, Saudi Arabia)
JID - 101252453
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Gas Analysis
MH  - Case-Control Studies
MH  - Evoked Potentials, Visual/*physiology
MH  - Female
MH  - Forced Expiratory Volume
MH  - Humans
MH  - Hypoxia/etiology/*physiopathology/therapy
MH  - Male
MH  - Middle Aged
MH  - Oxygen Inhalation Therapy
MH  - Patient Compliance
MH  - Prospective Studies
MH  - Pulmonary Disease, Chronic Obstructive/complications/*physiopathology/therapy
MH  - Respiratory Function Tests
MH  - Turkey
MH  - Vital Capacity
PMC - PMC5224407
EDAT- 2016/01/29 06:00
MHDA- 2016/07/16 06:00
PMCR- 2016/01/01
CRDT- 2016/01/29 06:00
PHST- 2016/01/29 06:00 [entrez]
PHST- 2016/01/29 06:00 [pubmed]
PHST- 2016/07/16 06:00 [medline]
PHST- 2016/01/01 00:00 [pmc-release]
AID - Neurosciences-21-26 [pii]
AID - 10.17712/nsj.2016.1.20150333 [doi]
PST - ppublish
SO  - Neurosciences (Riyadh). 2016 Jan;21(1):26-9. doi: 10.17712/nsj.2016.1.20150333.