PMID- 26826158
OWN - NLM
STAT- MEDLINE
DCOM- 20170630
LR  - 20171215
IS  - 1758-1052 (Electronic)
IS  - 0956-4624 (Linking)
VI  - 27
IP  - 11
DP  - 2016 Oct
TI  - Immune reconstitution inflammatory syndrome versus non-immune reconstitution 
      inflammatory syndrome lymphoma in HIV patients on antiretroviral therapy.
PG  - 1013-5
LID - 10.1177/0956462416630908 [doi]
AB  - Little is known about differences between immune reconstitution inflammatory 
      syndrome (IRIS) and non-IRIS lymphoma in HIV patients on antiretroviral therapy 
      (ART). The aim of this study was to describe the characteristics of IRIS and 
      non-IRIS lymphoma in Korean HIV-positive patients on ART compared with lymphoma 
      in those off ART. Of 1490 patients, 41 (3%) had lymphoma. Of these, 27 cases 
      (66%) were classified as lymphoma off ART, eight as IRIS lymphoma, and six as 
      non-IRIS lymphoma on ART. Hodgkin lymphoma was significantly more common among 
      patients with non-IRIS lymphoma on ART than among those with lymphoma off ART 
      (P = 0.005), whereas there was no Hodgkin lymphoma among IRIS lymphoma. Stage IV 
      lymphoma was significantly rarer in non-IRIS lymphoma on ART than in lymphoma off 
      ART (P = 0.007). Non-IRIS lymphoma on ART tends to have a better survival rate 
      than lymphoma off ART (Kaplan-Meier survival analysis, P = 0.167), while IRIS 
      lymphoma exhibited a survival rate similar to lymphoma off ART (P = 0.618). In 
      Korean HIV-positive patients, there were significantly more cases of Hodgkin 
      lymphoma of a less advanced stage in non-IRIS lymphoma on ART than in lymphoma 
      off ART, in contrast to IRIS lymphoma.
CI  - (c) The Author(s) 2016.
FAU - Choe, Pyoeng Gyun
AU  - Choe PG
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Park, Jinyong
AU  - Park J
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Park, Wan Beom
AU  - Park WB
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea wbpark1@snu.ac.kr.
FAU - Kim, Tae Min
AU  - Kim TM
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Song, Kyoung-Ho
AU  - Song KH
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Bang, Ji Hwan
AU  - Bang JH
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Kim, Eu Suk
AU  - Kim ES
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Park, Sang Won
AU  - Park SW
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Kim, Hong Bin
AU  - Kim HB
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Kim, Nam Joong
AU  - Kim NJ
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Oh, Myoung-Don
AU  - Oh MD
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Choe, Kang Won
AU  - Choe KW
AD  - Department of Internal Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
LA  - eng
PT  - Journal Article
DEP - 20160128
PL  - England
TA  - Int J STD AIDS
JT  - International journal of STD & AIDS
JID - 9007917
RN  - 0 (Anti-HIV Agents)
SB  - IM
MH  - AIDS-Related Opportunistic Infections/ethnology/*mortality
MH  - Adult
MH  - Anti-HIV Agents/*therapeutic use
MH  - *Antiretroviral Therapy, Highly Active
MH  - Female
MH  - HIV Infections/*complications/*drug therapy/ethnology
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*complications/ethnology/mortality
MH  - Incidence
MH  - Kaplan-Meier Estimate
MH  - Lymphoma, AIDS-Related/ethnology/*mortality
MH  - Lymphoma, Non-Hodgkin/ethnology/*mortality
MH  - Male
MH  - Republic of Korea/epidemiology
MH  - Severity of Illness Index
MH  - Survival Analysis
MH  - Viral Load
OTO - NOTNLM
OT  - AIDS
OT  - HIV
OT  - cancer
OT  - immune reconstitution inflammatory syndrome
OT  - lymphoma
EDAT- 2016/01/31 06:00
MHDA- 2017/07/01 06:00
CRDT- 2016/01/31 06:00
PHST- 2015/08/08 00:00 [received]
PHST- 2016/01/12 00:00 [accepted]
PHST- 2016/01/31 06:00 [entrez]
PHST- 2016/01/31 06:00 [pubmed]
PHST- 2017/07/01 06:00 [medline]
AID - 0956462416630908 [pii]
AID - 10.1177/0956462416630908 [doi]
PST - ppublish
SO  - Int J STD AIDS. 2016 Oct;27(11):1013-5. doi: 10.1177/0956462416630908. Epub 2016 
      Jan 28.