PMID- 26829725
OWN - NLM
STAT- MEDLINE
DCOM- 20160421
LR  - 20191210
IS  - 1003-9406 (Print)
IS  - 1003-9406 (Linking)
VI  - 33
IP  - 1
DP  - 2016 Feb
TI  - [Clinical significance of detecting t(11;14) by fluorescence in situ 
      hybridization for the diagnosis of 7 patients with atypical mantle cell 
      lymphoma].
PG  - 13-6
LID - 10.3760/cma.j.issn.1003-9406.2016.01.004 [doi]
AB  - OBJECTIVE: To study the clinical features and diagnosis of 7 patients with 
      atypical mantle cell lymphoma (MCL). METHODS: The 7 MCL patients were 
      misdiagnosed as chronic lymphocytic leukemia (CLL) due to a score of 4 for their 
      immunophenotypes. The clinical features and diagnosis of such patients were 
      retrospectively analyzed. RESULTS: Six patients had superficial lymphadenectasis 
      but their lymph nodes could not be palpated. All 7 patients were as stage IV 
      considering bone marrow infiltration. Scores of immunophenotype of CLL were 4, 
      and interphase fluorescence in situ hybridization (FISH) for t(11;14) were 
      positive in all patients. CONCLUSION: Some MCL patients have clinical features 
      similar to CLL. Interphase FISH can play an important role in the diagnosis of 
      MCL.
FAU - Zhu, Jianfeng
AU  - Zhu J
AD  - Department of Hematology, the People's Hospital of Taizhou, Nantong University, 
      Taizhou, Jiangsu 225300, China. lijianyonglm@medmail.com.cn.
FAU - Wu, Zhengdong
AU  - Wu Z
FAU - Fan, Lei
AU  - Fan L
FAU - Xu, Wei
AU  - Xu W
FAU - Li, Jianyong
AU  - Li J
LA  - chi
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi
JT  - Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese 
      journal of medical genetics
JID - 9425197
SB  - IM
MH  - Aged
MH  - Chromosomes, Human, Pair 11/*genetics
MH  - Chromosomes, Human, Pair 14/*genetics
MH  - Female
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/*methods
MH  - Lymphoma, Mantle-Cell/*diagnosis/*genetics
MH  - Male
MH  - Middle Aged
MH  - *Translocation, Genetic
EDAT- 2016/02/02 06:00
MHDA- 2016/04/22 06:00
CRDT- 2016/02/02 06:00
PHST- 2016/02/02 06:00 [entrez]
PHST- 2016/02/02 06:00 [pubmed]
PHST- 2016/04/22 06:00 [medline]
AID - 940632004 [pii]
AID - 10.3760/cma.j.issn.1003-9406.2016.01.004 [doi]
PST - ppublish
SO  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2016 Feb;33(1):13-6. doi: 
      10.3760/cma.j.issn.1003-9406.2016.01.004.