PMID- 26835022 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160202 LR - 20200930 IS - 2050-3369 (Print) IS - 2050-3377 (Electronic) IS - 2050-3369 (Linking) VI - 1 IP - 1 DP - 2012 Sep TI - Risk Stratification in Atrial Fibrillation Patients - A Review Focused on Mortality. PG - 8-11 LID - 10.15420/aer.2012.1.8 [doi] AB - Atrial fibrillation (AF) is associated with increased mortality that is largely due to the severe co-morbidities of patients with this rhythm disturbance rather than to its electrocardiographic features. Available evidence indicated that ageing, heart failure and stroke are the most important predictors of all-cause mortality. Additional clinical parameters such as smoking, renal impairment, chronic obstructive pulmonary disease may also identify patients at risk. The prevention of thromboembolic events is based on oral anticoagulant therapy, which reduces the severity and mortality of ischaemic strokes but slightly increase the rate of haemorrhagic events. Most of the traditional risk stratifiers commonly used in patients in sinus rhythm such as New York Heart Association (NYHA) functional class, left ventricular ejection fraction (LVEF) and resting heart rate seem to be less effective in AF patients thus leaving to the physician judgment the main responsibility of identifying patients with an increased mortality risk. FAU - Lombardi, Federico AU - Lombardi F AD - Professor of Cardiology; Director of Cardiology Unit, San Paolo Hospital, Department of Health Sciences, University of Milan, Italy. LA - eng PT - Journal Article PL - England TA - Arrhythm Electrophysiol Rev JT - Arrhythmia & electrophysiology review JID - 101637930 PMC - PMC4711547 OTO - NOTNLM OT - Arrhythmic mortality OT - ageing and arrhythmias OT - heart failure OT - stroke and arrhythmias EDAT- 2012/09/01 00:00 MHDA- 2012/09/01 00:01 PMCR- 2012/09/01 CRDT- 2016/02/03 06:00 PHST- 2016/02/03 06:00 [entrez] PHST- 2012/09/01 00:00 [pubmed] PHST- 2012/09/01 00:01 [medline] PHST- 2012/09/01 00:00 [pmc-release] AID - 10.15420/aer.2012.1.8 [doi] PST - ppublish SO - Arrhythm Electrophysiol Rev. 2012 Sep;1(1):8-11. doi: 10.15420/aer.2012.1.8.