PMID- 26835060 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160202 LR - 20200930 IS - 2050-3369 (Print) IS - 2050-3377 (Electronic) IS - 2050-3369 (Linking) VI - 3 IP - 1 DP - 2014 May TI - Use of Cardiac Resynchronisation Therapy - Change of Clinical Settings. PG - 20-4 LID - 10.15420/aer.2011.3.1.20 [doi] AB - Current guidelines recommend cardiac resynchronisation therapy (CRT) for patients with severe left ventricular dysfunction (left ventricular ejection fraction [LVEF] /=120-150 ms (Class IA and IB indications) on surface electrocardiogram (ECG) and New York Heart Association (NYHA) class III or IV heart failure (HF) symptoms. Ongoing studies aim to expand the use of CRT in patients with asymptomatic or minimal symptoms left ventricular dysfunction. There have been studies that have shown benefit of CRT extended to this group of patients. There have also been different implications of the role of CRT in patients with atrial fibrillation (AF), patients with narrow QRS duration or with right bundle branch block (RBBB) on surface ECG, as well as patients with end-stage renal failure on dialysis therapy. This article aims to review the current body of evidence of expanding use of CRT in these populations. FAU - Looi, Khang-Li AU - Looi KL AD - Cardiac Electrophysiology Fellow. FAU - Tang, Anthony Sl AU - Tang AS AD - Consultant Cardiologist and Electrophysiologist, London Health Science Centre, London, Ontario, Canada. FAU - Agarwal, Sharad AU - Agarwal S AD - Consultant Cardiologist and Electrophysiologist, Papworth Hospital NHS Foundation Trust, Cambridge, UK. LA - eng PT - Journal Article DEP - 20140530 PL - England TA - Arrhythm Electrophysiol Rev JT - Arrhythmia & electrophysiology review JID - 101637930 PMC - PMC4711514 OTO - NOTNLM OT - Cardiac resynchronisation therapy OT - New York Heart Association (NYHA) class OT - heart failure OT - left ventricular ejection fraction EDAT- 2014/05/01 00:00 MHDA- 2014/05/01 00:01 PMCR- 2014/06/01 CRDT- 2016/02/03 06:00 PHST- 2014/02/23 00:00 [received] PHST- 2014/03/24 00:00 [accepted] PHST- 2016/02/03 06:00 [entrez] PHST- 2014/05/01 00:00 [pubmed] PHST- 2014/05/01 00:01 [medline] PHST- 2014/06/01 00:00 [pmc-release] AID - 10.15420/aer.2011.3.1.20 [doi] PST - ppublish SO - Arrhythm Electrophysiol Rev. 2014 May;3(1):20-4. doi: 10.15420/aer.2011.3.1.20. Epub 2014 May 30.