PMID- 26835113 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160202 LR - 20200930 IS - 2050-3369 (Print) IS - 2050-3377 (Electronic) IS - 2050-3369 (Linking) VI - 4 IP - 2 DP - 2015 Aug TI - Developments in Cardiac Resynchronisation Therapy. PG - 122-8 LID - 10.15420/aer.2015.04.02.122 [doi] AB - Cardiac resynchronisation therapy (CRT) is an important therapy for patients with heart failure with a reduced ejection fraction and interventricular conduction delay. Large trials have established the role of CRT in reducing heart failure hospitalisations and improving symptoms, left ventricular (LV) function and mortality. Guidelines from major medical societies are consistent in support of CRT for patients with New York Health Association (NYHA) class II, III and ambulatory class IV heart failure, reduced LV ejection fraction and QRS prolongation, particularly left bundle branch block. The current challenge facing practitioners is to maximise the rate of patients who respond to CRT and the magnitude of that response. Current areas of interest for achieving these goals include tailoring patient selection, individualising LV lead placement and application of new technologies and techniques for CRT delivery. FAU - Lewis, Geoffrey F AU - Lewis GF AD - Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina, US. FAU - Gold, Michael R AU - Gold MR AD - Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina, US. LA - eng PT - Journal Article PL - England TA - Arrhythm Electrophysiol Rev JT - Arrhythmia & electrophysiology review JID - 101637930 PMC - PMC4711555 OTO - NOTNLM OT - Cardiac resynchronisation therapy OT - LV lead delivery OT - LV reverse remodelling OT - cardiac pacemaker OT - device programming OT - heart failure OT - implantable cardioverter/defibrillator OT - left bundle branch block OT - left ventricular function EDAT- 2016/02/03 06:00 MHDA- 2016/02/03 06:01 PMCR- 2015/09/01 CRDT- 2016/02/03 06:00 PHST- 2016/02/03 06:00 [entrez] PHST- 2016/02/03 06:00 [pubmed] PHST- 2016/02/03 06:01 [medline] PHST- 2015/09/01 00:00 [pmc-release] AID - 10.15420/aer.2015.04.02.122 [doi] PST - ppublish SO - Arrhythm Electrophysiol Rev. 2015 Aug;4(2):122-8. doi: 10.15420/aer.2015.04.02.122.