PMID- 26837498
OWN - NLM
STAT- MEDLINE
DCOM- 20161024
LR  - 20181202
IS  - 1534-3170 (Electronic)
IS  - 1523-3782 (Linking)
VI  - 18
IP  - 3
DP  - 2016 Mar
TI  - Does Surgical Repair of Moderate Ischemic Mitral Regurgitation Improve Survival? 
      A Systematic Review.
PG  - 22
LID - 10.1007/s11886-016-0701-5 [doi]
AB  - Mitral regurgitation (MR) is one of the common complications in myocardial 
      infarction (MI) patients. Almost half of the post MI patients have MR (ischemic 
      MR)(17) which is moderate to severe (grade II-IV). Whether there is a mortality 
      benefit of performing mitral valve repair (MVR) along with coronary artery bypass 
      grafting (CABG) in patients with post MI moderate MR remains inconclusive. 
      Literature search was done from PubMed, Google scholar, Ovid, and Medline 
      databases. Studies which included post MI patients with moderate ischemic MR and 
      reported mortality outcomes of performing CABG and MVR were chosen for the 
      systematic review. Our preliminary literature search identified 194 studies, of 
      which 11 studies met our inclusion criteria. Nine studies showed no survival 
      benefit of performing simultaneous MVR and CABG. One study demonstrated survival 
      benefit of performing CABG plus MVR only in the New York Heart Association (NYHA) 
      class III-IV, and one study suggested survival benefit of performing CABG plus 
      MVR as compared to CABG alone in patient with ischemic MR irrespective of 
      preoperative NYHA functional class. Review of current literature showed mixed 
      results in terms of improvement in functional status but failed to show any 
      survival benefit of performing MVR along with CABG. Limitations of studies 
      include small sample size, difference in baseline demographic variables, and 
      short follow-up period which might influence the outcome of the study. 
      Prospective randomized studies are required to establish clear benefit of 
      performing MVR simultaneously with CABG.
FAU - Chatterjee, Saurav
AU  - Chatterjee S
AD  - Cardiovascular Diseases, Division of Cardiology, Mount Sinai St. Luke's Roosevelt 
      Hospitals, 1111 Amsterdam Avenue, Clark building 3rd floor, New York, NY, 10025, 
      USA. schatterjee@chpnet.org.
FAU - Tripathi, Byomesh
AU  - Tripathi B
AD  - Cardiovascular Diseases, Division of Cardiology, Mount Sinai St. Luke's Roosevelt 
      Hospitals, 1111 Amsterdam Avenue, Clark building 3rd floor, New York, NY, 10025, 
      USA.
FAU - Virk, Hafeez Ul Hassan
AU  - Virk HU
AD  - Cardiovascular Diseases, Division of Cardiology, Mount Sinai St. Luke's Roosevelt 
      Hospitals, 1111 Amsterdam Avenue, Clark building 3rd floor, New York, NY, 10025, 
      USA.
FAU - Ahmed, Mohammed
AU  - Ahmed M
AD  - Cardiovascular Diseases, Division of Cardiology, Mount Sinai St. Luke's Roosevelt 
      Hospitals, 1111 Amsterdam Avenue, Clark building 3rd floor, New York, NY, 10025, 
      USA.
FAU - Bavishi, Chirag
AU  - Bavishi C
AD  - Cardiovascular Diseases, Division of Cardiology, Mount Sinai St. Luke's Roosevelt 
      Hospitals, 1111 Amsterdam Avenue, Clark building 3rd floor, New York, NY, 10025, 
      USA.
FAU - Krishnamoorthy, Parasuram
AU  - Krishnamoorthy P
AD  - Division of Cardiology, Albert Einstein Medical Center, Philadelphia, PA, USA.
FAU - Sardar, Partha
AU  - Sardar P
AD  - Division of Cardiology, University of Utah, Salt Lake City, UT, USA.
FAU - Giri, Jay
AU  - Giri J
AD  - Division of Cardiology, Perelman School of Medicine, University of Pennsylvania, 
      Philadelphia, PA, USA.
FAU - Omidvari, Karan
AU  - Omidvari K
AD  - Cardiovascular Diseases, Division of Cardiology, Mount Sinai St. Luke's Roosevelt 
      Hospitals, 1111 Amsterdam Avenue, Clark building 3rd floor, New York, NY, 10025, 
      USA.
AD  - Department of Cardiothoracic Surgery, Icahn School of Medicine, Mount Sinai St. 
      Luke's Roosevelt Hospital, New York, NY, USA.
FAU - Chikwe, Joanna
AU  - Chikwe J
AD  - Cardiovascular Diseases, Division of Cardiology, Mount Sinai St. Luke's Roosevelt 
      Hospitals, 1111 Amsterdam Avenue, Clark building 3rd floor, New York, NY, 10025, 
      USA.
AD  - Department of Cardiothoracic Surgery, Icahn School of Medicine, Mount Sinai St. 
      Luke's Roosevelt Hospital, New York, NY, USA.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
PL  - United States
TA  - Curr Cardiol Rep
JT  - Current cardiology reports
JID - 100888969
SB  - IM
MH  - Coronary Artery Bypass
MH  - Heart Valve Prosthesis Implantation
MH  - Humans
MH  - Mitral Valve Insufficiency/etiology/mortality/*surgery
MH  - Myocardial Infarction/complications/mortality/surgery
MH  - Survival Analysis
OTO - NOTNLM
OT  - Moderate ischemic mitral regurgitation
OT  - Surgical repair
OT  - Systemic review
EDAT- 2016/02/04 06:00
MHDA- 2016/10/25 06:00
CRDT- 2016/02/04 06:00
PHST- 2016/02/04 06:00 [entrez]
PHST- 2016/02/04 06:00 [pubmed]
PHST- 2016/10/25 06:00 [medline]
AID - 10.1007/s11886-016-0701-5 [pii]
AID - 10.1007/s11886-016-0701-5 [doi]
PST - ppublish
SO  - Curr Cardiol Rep. 2016 Mar;18(3):22. doi: 10.1007/s11886-016-0701-5.