PMID- 26843100 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160624 LR - 20160219 IS - 1523-7052 (Electronic) IS - 1523-7052 (Linking) VI - 18 IP - 4 DP - 2016 Feb 19 TI - Approach to Isoindolinones, Isoquinolinones, and THIQs via Lewis Acid-Catalyzed Domino Strecker-Lactamization/Alkylations. PG - 634-7 LID - 10.1021/acs.orglett.5b03331 [doi] AB - A one-pot, three-component synthesis of widely substituted isoindolinones and isoquinolinones, featuring a Lewis acid-catalyzed efficient Strecker reaction and lactamization sequence, affording products in good to high yields is reported. The method has also been extended to the synthesis of tetrahydroisoquinolines (THIQs) in high yields. FAU - Dhanasekaran, Sivasankaran AU - Dhanasekaran S AD - Department of Chemistry, Indian Institute of Technology , Kanpur, UP - 208 016, India. FAU - Suneja, Arun AU - Suneja A AD - Department of Chemistry, Indian Institute of Science Education and Research , Bhopal, MP - 462 066, India. FAU - Bisai, Vishnumaya AU - Bisai V AD - Department of Chemistry, Indian Institute of Science Education and Research , Bhopal, MP - 462 066, India. FAU - Singh, Vinod K AU - Singh VK AD - Department of Chemistry, Indian Institute of Science Education and Research , Bhopal, MP - 462 066, India. AD - Department of Chemistry, Indian Institute of Technology , Kanpur, UP - 208 016, India. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20160204 PL - United States TA - Org Lett JT - Organic letters JID - 100890393 EDAT- 2016/02/05 06:00 MHDA- 2016/02/05 06:01 CRDT- 2016/02/05 06:00 PHST- 2016/02/05 06:00 [entrez] PHST- 2016/02/05 06:00 [pubmed] PHST- 2016/02/05 06:01 [medline] AID - 10.1021/acs.orglett.5b03331 [doi] PST - ppublish SO - Org Lett. 2016 Feb 19;18(4):634-7. doi: 10.1021/acs.orglett.5b03331. Epub 2016 Feb 4.