PMID- 26847076
OWN - NLM
STAT- MEDLINE
DCOM- 20170807
LR  - 20220317
IS  - 1532-2092 (Electronic)
IS  - 1099-5129 (Print)
IS  - 1099-5129 (Linking)
VI  - 18
IP  - 9
DP  - 2016 Sep
TI  - Battery drain in daily practice and medium-term projections on longevity of 
      cardioverter-defibrillators: an analysis from a remote monitoring database.
PG  - 1366-73
LID - 10.1093/europace/euv436 [doi]
AB  - AIMS: The longevity of generators is a crucial determinant of the 
      cost-effectiveness of therapy with implantable cardioverter-defibrillators (ICDs) 
      and cardiac resynchronization therapy defibrillators (CRT-D). We evaluated the 
      trend of device-measured residual battery capacity and longevity projections over 
      5-year follow-up. We also investigated possible factors associated with battery 
      drain. METHODS AND RESULTS: Data from 4851 patients in the European LATITUDE((R)) 
      database who were followed up for a minimum of 3 years were analysed. The factors 
      associated with battery drain (i.e. year-to-year decrease in residual battery 
      capacity), and thus potentially impacting on device longevity, were mainly the 
      pacing parameters in CRT-D devices and the number of shocks delivered and 
      diverted in both ICD and CRT-D (all P < 0.01 on linear regression analysis). Over 
      the first 5 years, the longevity estimates provided by devices showed low 
      intra-patient variability and increased with time. The estimates exceeded 10 
      years for CRT-D and 13 and 12 years for single- and dual-chamber ICDs, 
      respectively. In CRT-D patients, the expected patient age on replacement was 80 +/- 
      12 years, and the expected probability of undergoing device replacement was 63 +/- 
      13% for New York Heart Association (NYHA) II patients and 37 +/- 16% for NYHA III 
      patients. For comparison, the probabilities of replacing a CRT-D lasting 5 years 
      were 78 +/- 8 and 59 +/- 13%, respectively (both P < 0.001). CONCLUSION: Battery 
      drain was mainly associated with pacing output in CRT-D devices and with the 
      number of capacitor charges in both ICD and CRT-D devices. The longevity 
      estimates provided by the devices were consistent and conservative. According to 
      these estimates, among CRT-D recipients a low proportion of patients should 
      require device replacement.
CI  - (c) The Author 2016. Published by Oxford University Press on behalf of the European 
      Society of Cardiology.
FAU - Boriani, Giuseppe
AU  - Boriani G
AD  - Institute of Cardiology, University of Bologna and Azienda Ospedaliera 
      S.Orsola-Malpighi, Bologna, Italy Department of Cardiology, University of Modena 
      and Reggio Emilia, Policlinico di Modena, Modena, Italy 
      giuseppe.boriani@unimore.it.
FAU - Ritter, Philippe
AU  - Ritter P
AD  - Hopital Cardiologique du Haut-Leveque, CHU de Bordeaux, France.
FAU - Biffi, Mauro
AU  - Biffi M
AD  - Institute of Cardiology, University of Bologna and Azienda Ospedaliera 
      S.Orsola-Malpighi, Bologna, Italy.
FAU - Ziacchi, Matteo
AU  - Ziacchi M
AD  - Institute of Cardiology, University of Bologna and Azienda Ospedaliera 
      S.Orsola-Malpighi, Bologna, Italy.
FAU - Diemberger, Igor
AU  - Diemberger I
AD  - Institute of Cardiology, University of Bologna and Azienda Ospedaliera 
      S.Orsola-Malpighi, Bologna, Italy.
FAU - Martignani, Cristian
AU  - Martignani C
AD  - Institute of Cardiology, University of Bologna and Azienda Ospedaliera 
      S.Orsola-Malpighi, Bologna, Italy.
FAU - Valzania, Cinzia
AU  - Valzania C
AD  - Institute of Cardiology, University of Bologna and Azienda Ospedaliera 
      S.Orsola-Malpighi, Bologna, Italy.
FAU - Valsecchi, Sergio
AU  - Valsecchi S
AD  - Boston Scientific Italia, Milan, Italy.
FAU - Padeletti, Luigi
AU  - Padeletti L
AD  - University of Florence, Florence, Italy IRCCS MultiMedica, Sesto San Giovanni, 
      Italy.
FAU - Gadler, Fredrik
AU  - Gadler F
AD  - Karolinska University Hospital, Stockholm, Sweden.
LA  - eng
PT  - Journal Article
DEP - 20160203
PL  - England
TA  - Europace
JT  - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal 
      of the working groups on cardiac pacing, arrhythmias, and cardiac cellular 
      electrophysiology of the European Society of Cardiology
JID - 100883649
SB  - IM
CIN - Europace. 2016 Sep;18(9):1285-6. PMID: 26941342
MH  - *Cardiac Resynchronization Therapy/adverse effects/trends
MH  - *Cardiac Resynchronization Therapy Devices/adverse effects/trends
MH  - Chi-Square Distribution
MH  - Databases, Factual
MH  - *Defibrillators, Implantable/adverse effects/trends
MH  - Device Removal
MH  - Electric Countershock/adverse effects/*instrumentation/trends
MH  - *Electric Power Supplies/adverse effects/trends
MH  - Humans
MH  - Linear Models
MH  - Prosthesis Design
MH  - *Prosthesis Failure/trends
MH  - *Remote Sensing Technology/trends
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
PMC - PMC5006961
OTO - NOTNLM
OT  - Battery
OT  - Cardiac resynchronization therapy
OT  - Implantable cardioverter-defibrillator
OT  - Longevity
OT  - Remote monitoring
EDAT- 2016/02/06 06:00
MHDA- 2017/08/08 06:00
PMCR- 2016/02/03
CRDT- 2016/02/06 06:00
PHST- 2015/10/01 00:00 [received]
PHST- 2015/12/02 00:00 [accepted]
PHST- 2016/02/06 06:00 [entrez]
PHST- 2016/02/06 06:00 [pubmed]
PHST- 2017/08/08 06:00 [medline]
PHST- 2016/02/03 00:00 [pmc-release]
AID - euv436 [pii]
AID - 10.1093/europace/euv436 [doi]
PST - ppublish
SO  - Europace. 2016 Sep;18(9):1366-73. doi: 10.1093/europace/euv436. Epub 2016 Feb 3.