PMID- 26848563
OWN - NLM
STAT- MEDLINE
DCOM- 20171120
LR  - 20171128
IS  - 1098-8947 (Electronic)
IS  - 0743-684X (Linking)
VI  - 32
IP  - 6
DP  - 2016 Jul
TI  - Complications and Risk after Mandibular Reconstruction with Fibular Free Flaps in 
      Patients with Oral Squamous Cell Carcinoma: A Retrospective Cohort Study.
PG  - 455-63
LID - 10.1055/s-0036-1571794 [doi]
AB  - Background We retrospectively analyzed the incidence and types of postoperative 
      complications after mandibular continuity reconstructions with fibular free flaps 
      (FFF) in patients with oral squamous cell carcinoma (OSCC) and identified 
      potential risk factors for postoperative complications. Methods Data were 
      retrieved from the medical records in the Department of Oral and Maxillofacial 
      Surgery/Oral Pathology, VU University Medical Center/Academic Centre for 
      Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands from April 1995 to 
      September 2013, and were statistically analyzed. Results In this study, 85 
      patients were included in whom 86 FFFs were used for mandibular reconstruction. 
      Thirty-seven patients (43%) developed >/= 1 surgical complication and 9 patients 
      (10.5%) developed >/= 1 systemic complication. Three patients (3.5%) developed 
      total flap failure and six patients (7.0%) developed partial flap failure. 
      Surgical complications were correlated with tobacco use, partial glossectomy, 
      type of mandibular defect, and anatomic staging. Systemic complications were 
      associated with age > 60 years and Charlson comorbidity index > 2. 
      Hospitalization > 30 days was associated with type of mandibular defect. 
      Conclusions The use of the FFF for reconstructing mandibular continuity defects 
      in OSCC patients may be associated with postoperative complications. Patients 
      with coexisting medical conditions and anterior mandibular defects have an 
      increased risk for developing complications. Patients who undergo segmental 
      mandibular resection including a partial glossectomy could have a reduced risk 
      for complications.
CI  - Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
FAU - Lodders, J N
AU  - Lodders JN
AD  - Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University 
      Medical Center/Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The 
      Netherlands.
FAU - Schulten, E A J M
AU  - Schulten EA
AD  - Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University 
      Medical Center/Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The 
      Netherlands.
FAU - de Visscher, J G A M
AU  - de Visscher JG
AD  - Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University 
      Medical Center/Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The 
      Netherlands.
FAU - Forouzanfar, T
AU  - Forouzanfar T
AD  - Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University 
      Medical Center/Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The 
      Netherlands.
FAU - Karagozoglu, K H
AU  - Karagozoglu KH
AD  - Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University 
      Medical Center/Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The 
      Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20160205
PL  - United States
TA  - J Reconstr Microsurg
JT  - Journal of reconstructive microsurgery
JID - 8502670
SB  - IM
CIN - J Reconstr Microsurg. 2017 Jun;33(5):377-378. PMID: 28561187
CIN - J Reconstr Microsurg. 2017 Jun;33(5):379-380. PMID: 28561188
MH  - Bone Transplantation/methods
MH  - Carcinoma, Squamous Cell/pathology
MH  - Comorbidity
MH  - Female
MH  - Fibula/pathology/*transplantation
MH  - Free Tissue Flaps/*blood supply
MH  - Graft Survival
MH  - Humans
MH  - Male
MH  - Mandibular Neoplasms/pathology/*surgery
MH  - *Mandibular Reconstruction/adverse effects/methods
MH  - Middle Aged
MH  - Netherlands
MH  - Postoperative Complications/pathology/*surgery
MH  - Quality of Life
MH  - Retrospective Studies
MH  - Tobacco Use/*adverse effects
MH  - Treatment Outcome
EDAT- 2016/02/06 06:00
MHDA- 2017/11/29 06:00
CRDT- 2016/02/06 06:00
PHST- 2016/02/06 06:00 [entrez]
PHST- 2016/02/06 06:00 [pubmed]
PHST- 2017/11/29 06:00 [medline]
AID - 10.1055/s-0036-1571794 [doi]
PST - ppublish
SO  - J Reconstr Microsurg. 2016 Jul;32(6):455-63. doi: 10.1055/s-0036-1571794. Epub 
      2016 Feb 5.