PMID- 26853871 OWN - NLM STAT- MEDLINE DCOM- 20160614 LR - 20160208 IS - 0289-0003 (Print) IS - 0289-0003 (Linking) VI - 33 IP - 1 DP - 2016 Feb TI - Whole Genome Re-Sequencing of Three Domesticated Chicken Breeds. PG - 73-7 LID - 10.2108/zs150071 [doi] AB - Chicken is one of the most popular domesticated species worldwide, as it can serve an important role in agricultural as well as biomedical research fields. Because it inhabits almost every continent and presents diverse morphology and traits, the need of genetic markers for distinguishing each breed for various purposes has increased. The whole genome sequencing of three different breeds (White Leghorn, Korean domestic, and Araucana) that show similar coloring patterns, with the exception of the White Leghorn breed, have confirmed previously reported genomic alterations and identified many novel variants. Additionally, the Whole Genome Re-Sequencing (WGRS) approach identified an approximately 4 kb insert within SLCO1B3 responsible for blue egg shell color. Targeted investigation of pigment-related genes corroborated previously reported non-synonymous mutations, and provided deeper insight into chicken coloring, where not a single but a combination of non-synonymous mutations in the MC1R gene is likely to be responsible for altered feather coloring. FAU - Oh, Dongyep AU - Oh D AD - 1 Livestock Research institute, Gyeongsangbuk-Do, Yeongju, Gyeongbuk, 750-871, Republic of Korea. FAU - Son, Bongjun AU - Son B AD - 2 Theragen BiO institute, TheragenEtex, Suwon, Gyueonggi-do, 443-270, Republic of Korea. FAU - Mun, Seyoung AU - Mun S AD - 3 Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dan kook University, Cheonan, 330-714, Republic of Korea. AD - 4 DKU-Theragen institute for NGS analysis (DTiNa), Cheonan, 330-714, Republic of Korea. FAU - Oh, Man Hwan AU - Oh MH AD - 3 Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dan kook University, Cheonan, 330-714, Republic of Korea. FAU - Oh, Sejong AU - Oh S AD - 3 Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dan kook University, Cheonan, 330-714, Republic of Korea. FAU - Ha, Jaejung AU - Ha J AD - 1 Livestock Research institute, Gyeongsangbuk-Do, Yeongju, Gyeongbuk, 750-871, Republic of Korea. FAU - Yi, Junkoo AU - Yi J AD - 1 Livestock Research institute, Gyeongsangbuk-Do, Yeongju, Gyeongbuk, 750-871, Republic of Korea. FAU - Lee, Seunguk AU - Lee S AD - 5 Biotechnology Research Center, University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, Japan. FAU - Han, Kyudong AU - Han K AD - 3 Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dan kook University, Cheonan, 330-714, Republic of Korea. AD - 4 DKU-Theragen institute for NGS analysis (DTiNa), Cheonan, 330-714, Republic of Korea. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Japan TA - Zoolog Sci JT - Zoological science JID - 8702287 RN - 0 (Organic Anion Transporters, Sodium-Independent) RN - 0 (Pigments, Biological) RN - 0 (Receptor, Melanocortin, Type 1) SB - IM MH - Animals MH - Chickens/*genetics MH - Feathers/physiology MH - Gene Expression Regulation/physiology MH - *Genetic Variation MH - *Genome MH - Organic Anion Transporters, Sodium-Independent/genetics/metabolism MH - Phylogeny MH - Pigments, Biological MH - Receptor, Melanocortin, Type 1/genetics/metabolism OTO - NOTNLM OT - Araucana OT - Korean cattle OT - Korean domestic OT - MC1R OT - SLCO1B3 OT - White Leghorn EDAT- 2016/02/09 06:00 MHDA- 2016/06/15 06:00 CRDT- 2016/02/09 06:00 PHST- 2016/02/09 06:00 [entrez] PHST- 2016/02/09 06:00 [pubmed] PHST- 2016/06/15 06:00 [medline] AID - 10.2108/zs150071 [doi] PST - ppublish SO - Zoolog Sci. 2016 Feb;33(1):73-7. doi: 10.2108/zs150071.