PMID- 26856788 OWN - NLM STAT- MEDLINE DCOM- 20161226 LR - 20191210 IS - 1879-291X (Electronic) IS - 0301-5629 (Linking) VI - 42 IP - 5 DP - 2016 May TI - A Broadband Polyvinylidene Difluoride-Based Hydrophone with Integrated Readout Circuit for Intravascular Photoacoustic Imaging. PG - 1239-43 LID - S0301-5629(15)00740-1 [pii] LID - 10.1016/j.ultrasmedbio.2015.12.016 [doi] AB - Intravascular photoacoustic (IVPA) imaging can visualize the coronary atherosclerotic plaque composition on the basis of the optical absorption contrast. Most of the photoacoustic (PA) energy of human coronary plaque lipids was found to lie in the frequency band between 2 and 15 MHz requiring a very broadband transducer, especially if a combination with intravascular ultrasound is desired. We have developed a broadband polyvinylidene difluoride (PVDF) transducer (0.6 x 0.6 mm, 52 mum thick) with integrated electronics to match the low capacitance of such a small polyvinylidene difluoride element (<5 pF/mm(2)) with the high capacitive load of the long cable ( approximately 100 pF/m). The new readout circuit provides an output voltage with a sensitivity of about 3.8 muV/Pa at 2.25 MHz. Its response is flat within 10 dB in the range 2 to 15 MHz. The root mean square (rms) output noise level is 259 muV over the entire bandwidth (1-20 MHz), resulting in a minimum detectable pressure of 30 Pa at 2.25 MHz. CI - Copyright (c) 2016 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved. FAU - Daeichin, Verya AU - Daeichin V AD - Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, The Netherlands. Electronic address: v.daeichin@erasmusmc.nl. FAU - Chen, Chao AU - Chen C AD - Electronic Instrumentation Lab, Delft University of Technology, Delft, The Netherlands. FAU - Ding, Qing AU - Ding Q AD - Electronic Instrumentation Lab, Delft University of Technology, Delft, The Netherlands. FAU - Wu, Min AU - Wu M AD - Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, The Netherlands. FAU - Beurskens, Robert AU - Beurskens R AD - Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, The Netherlands. FAU - Springeling, Geert AU - Springeling G AD - Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, The Netherlands. FAU - Noothout, Emile AU - Noothout E AD - Lab of Acoustical Wavefield Imaging, Delft University of Technology, Delft, The Netherlands. FAU - Verweij, Martin D AU - Verweij MD AD - Lab of Acoustical Wavefield Imaging, Delft University of Technology, Delft, The Netherlands. FAU - van Dongen, Koen W A AU - van Dongen KW AD - Lab of Acoustical Wavefield Imaging, Delft University of Technology, Delft, The Netherlands. FAU - Bosch, Johan G AU - Bosch JG AD - Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, The Netherlands. FAU - van der Steen, Antonius F W AU - van der Steen AF AD - Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, The Netherlands; Lab of Acoustical Wavefield Imaging, Delft University of Technology, Delft, The Netherlands. FAU - de Jong, Nico AU - de Jong N AD - Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, The Netherlands; Lab of Acoustical Wavefield Imaging, Delft University of Technology, Delft, The Netherlands. FAU - Pertijs, Michiel AU - Pertijs M AD - Electronic Instrumentation Lab, Delft University of Technology, Delft, The Netherlands. FAU - van Soest, Gijs AU - van Soest G AD - Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, The Netherlands. LA - eng PT - Evaluation Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20160205 PL - England TA - Ultrasound Med Biol JT - Ultrasound in medicine & biology JID - 0410553 RN - 0 (Polyvinyls) RN - 24937-79-9 (polyvinylidene fluoride) SB - IM MH - Amplifiers, Electronic MH - Elasticity Imaging Techniques/*instrumentation MH - Equipment Design MH - Equipment Failure Analysis MH - Image Enhancement/instrumentation MH - Image Interpretation, Computer-Assisted/instrumentation MH - Micro-Electrical-Mechanical Systems/*instrumentation MH - Polyvinyls/*chemistry/radiation effects MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Signal Processing, Computer-Assisted/*instrumentation MH - Systems Integration MH - *Transducers MH - Ultrasonic Waves MH - Ultrasonography, Interventional/*instrumentation MH - User-Computer Interface OTO - NOTNLM OT - Atherosclerosis OT - Broadband receiver OT - Hydrophone OT - Integrated circuit OT - Photoacoustic OT - Polyvinylidene difluoride transducer EDAT- 2016/02/10 06:00 MHDA- 2016/12/27 06:00 CRDT- 2016/02/10 06:00 PHST- 2015/07/16 00:00 [received] PHST- 2015/10/21 00:00 [revised] PHST- 2015/12/16 00:00 [accepted] PHST- 2016/02/10 06:00 [entrez] PHST- 2016/02/10 06:00 [pubmed] PHST- 2016/12/27 06:00 [medline] AID - S0301-5629(15)00740-1 [pii] AID - 10.1016/j.ultrasmedbio.2015.12.016 [doi] PST - ppublish SO - Ultrasound Med Biol. 2016 May;42(5):1239-43. doi: 10.1016/j.ultrasmedbio.2015.12.016. Epub 2016 Feb 5.