PMID- 26857836
OWN - NLM
STAT- MEDLINE
DCOM- 20160706
LR  - 20181202
IS  - 1539-3704 (Electronic)
IS  - 0003-4819 (Linking)
VI  - 164
IP  - 5
DP  - 2016 Mar 1
TI  - Screening for Major Depressive Disorder in Children and Adolescents: A Systematic 
      Review for the U.S. Preventive Services Task Force.
PG  - 342-9
LID - 10.7326/M15-2259 [doi]
AB  - BACKGROUND: Major depressive disorder (MDD) is common among children and 
      adolescents and is associated with functional impairment and suicide. PURPOSE: To 
      update the 2009 U.S. Preventive Services Task Force (USPSTF) systematic review on 
      screening for and treatment of MDD in children and adolescents in primary care 
      settings. DATA SOURCES: Several electronic searches (May 2007 to February 2015) 
      and searches of reference lists of published literature. STUDY SELECTION: Trials 
      and recent systematic reviews of treatment, test-retest studies of screening, and 
      trials and large cohort studies for harms. DATA EXTRACTION: Data were abstracted 
      by 1 investigator and checked by another; 2 investigators independently assessed 
      study quality. DATA SYNTHESIS: Limited evidence from 5 studies showed that such 
      tools as the Beck Depression Inventory and Patient Health Questionnaire for 
      Adolescents had reasonable accuracy for identifying MDD among adolescents in 
      primary care settings. Six trials evaluated treatment. Several individual fair- 
      and good-quality studies of fluoxetine, combined fluoxetine and cognitive 
      behavioral therapy, escitalopram, and collaborative care demonstrated benefits of 
      treatment among adolescents, with no associated harms. LIMITATION: The review 
      included only English-language studies, narrow inclusion criteria focused only on 
      MDD, high thresholds for quality, potential publication bias, limited data on 
      harms, and sparse evidence on long-term outcomes of screening and treatment among 
      children younger than 12 years. CONCLUSION: No evidence was found of a direct 
      link between screening children and adolescents for MDD in primary care or 
      similar settings and depression or other health-related outcomes. Evidence showed 
      that some screening tools are accurate and some treatments are beneficial among 
      adolescents (but not younger children), with no evidence of associated harms. 
      PRIMARY FUNDING SOURCE: Agency for Healthcare Research and Quality.
FAU - Forman-Hoffman, Valerie
AU  - Forman-Hoffman V
FAU - McClure, Emily
AU  - McClure E
FAU - McKeeman, Joni
AU  - McKeeman J
FAU - Wood, Charles T
AU  - Wood CT
FAU - Middleton, Jennifer Cook
AU  - Middleton JC
FAU - Skinner, Asheley C
AU  - Skinner AC
FAU - Perrin, Eliana M
AU  - Perrin EM
FAU - Viswanathan, Meera
AU  - Viswanathan M
LA  - eng
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Review
PT  - Systematic Review
DEP - 20160209
PL  - United States
TA  - Ann Intern Med
JT  - Annals of internal medicine
JID - 0372351
SB  - IM
SPIN- Ann Intern Med. 2016 Mar 1;164(5). doi: 10.7326/P16-9006. PMID: 26856311
MH  - Adolescent
MH  - Child
MH  - Depressive Disorder, Major/*diagnosis/psychology/*therapy
MH  - Humans
MH  - *Mass Screening/adverse effects
MH  - Primary Health Care
MH  - Suicide
MH  - United States
EDAT- 2016/02/10 06:00
MHDA- 2016/07/07 06:00
CRDT- 2016/02/10 06:00
PHST- 2016/02/10 06:00 [entrez]
PHST- 2016/02/10 06:00 [pubmed]
PHST- 2016/07/07 06:00 [medline]
AID - 2490526 [pii]
AID - 10.7326/M15-2259 [doi]
PST - ppublish
SO  - Ann Intern Med. 2016 Mar 1;164(5):342-9. doi: 10.7326/M15-2259. Epub 2016 Feb 9.