PMID- 26869330
OWN - NLM
STAT- MEDLINE
DCOM- 20170714
LR  - 20181113
IS  - 1615-6692 (Electronic)
IS  - 0340-9937 (Linking)
VI  - 41
IP  - 6
DP  - 2016 Sep
TI  - [Hemodynamics and physical capacity in patients with left ventricular assist 
      devices : An overview].
PG  - 507-13
LID - 10.1007/s00059-015-4396-y [doi]
AB  - In the course of time implantation of left ventricular assist devices (LVAD) has 
      become an alternative to heart transplantation due to the enormous technical 
      developments and miniaturization of these systems. Following implantation most 
      patients show a significant improvement in their clinical condition and exercise 
      capacity as measured by the New York Heart Association (NYHA) classification; 
      nevertheless, exercise tolerance remains clearly limited even after LVAD 
      implantation. The complex physiological and hemodynamic changes in LVAD patients 
      both at rest and during exercise are ultimately not completely understood. The 
      aim of this article is to describe the current state of scientific knowledge with 
      respect to the physical capacity of patients with terminal heart failure after 
      LVAD implantation at rest and during exercise. The influence of increasing the 
      pump speed and continuous physical exercise training on the physical capacity in 
      the long-term course is reviewed. The significance of new diagnostic tools, such 
      as the non-invasive inert gas rebreathing method for measurement of cardiac 
      output and arteriovenous oxygen difference (AVDO2) in assessment of the 
      performance of LVAD patients is discussed.
FAU - Reiss, N
AU  - Reiss N
AD  - Abteilung fur Klinische Forschung, Klinik fur Rehabilitation, Bad Rothenfelde, 
      Deutschland. nreiss@schuechtermann-klinik.de.
AD  - Klinik fur Herzchirurgie, Schuchtermann-Klinik, Bad Rothenfelde, Deutschland. 
      nreiss@schuechtermann-klinik.de.
FAU - Altesellmeier, M
AU  - Altesellmeier M
AD  - Abteilung fur Klinische Forschung, Klinik fur Rehabilitation, Bad Rothenfelde, 
      Deutschland.
FAU - Mommertz, S
AU  - Mommertz S
AD  - Abteilung fur Klinische Forschung, Klinik fur Rehabilitation, Bad Rothenfelde, 
      Deutschland.
FAU - Schmidt, T
AU  - Schmidt T
AD  - Abteilung fur Klinische Forschung, Klinik fur Rehabilitation, Bad Rothenfelde, 
      Deutschland.
FAU - Schulte-Eistrup, S
AU  - Schulte-Eistrup S
AD  - Klinik fur Herzchirurgie, Schuchtermann-Klinik, Bad Rothenfelde, Deutschland.
FAU - Willemsen, D
AU  - Willemsen D
AD  - Abteilung fur Klinische Forschung, Klinik fur Rehabilitation, Bad Rothenfelde, 
      Deutschland.
LA  - ger
PT  - Journal Article
PT  - Review
TT  - Hamodynamik und korperliche Belastbarkeit bei Patienten mit 
      Linksherzunterstutzungssystem : Ein Uberblick.
DEP - 20160211
PL  - Germany
TA  - Herz
JT  - Herz
JID - 7801231
SB  - IM
MH  - Evidence-Based Medicine
MH  - Exercise Test
MH  - *Exercise Tolerance
MH  - Heart Failure/diagnosis/*physiopathology/*therapy
MH  - *Heart-Assist Devices
MH  - Humans
MH  - Recovery of Function/*physiology
MH  - Treatment Outcome
MH  - Ventricular Function, Left/*physiology
OTO - NOTNLM
OT  - Heart failure
OT  - Hemodynamics
OT  - Inert gas rebreathing
OT  - Left ventricular assist device
OT  - Physical capacity
EDAT- 2016/02/13 06:00
MHDA- 2017/07/15 06:00
CRDT- 2016/02/13 06:00
PHST- 2015/10/22 00:00 [received]
PHST- 2015/12/12 00:00 [accepted]
PHST- 2015/12/02 00:00 [revised]
PHST- 2016/02/13 06:00 [entrez]
PHST- 2016/02/13 06:00 [pubmed]
PHST- 2017/07/15 06:00 [medline]
AID - 10.1007/s00059-015-4396-y [pii]
AID - 10.1007/s00059-015-4396-y [doi]
PST - ppublish
SO  - Herz. 2016 Sep;41(6):507-13. doi: 10.1007/s00059-015-4396-y. Epub 2016 Feb 11.