PMID- 26869680
OWN - NLM
STAT- MEDLINE
DCOM- 20160907
LR  - 20210109
IS  - 2051-817X (Print)
IS  - 2051-817X (Electronic)
IS  - 2051-817X (Linking)
VI  - 4
IP  - 3
DP  - 2016 Feb
TI  - A 3-week multimodal intervention involving high-intensity interval training in 
      female cancer survivors: a randomized controlled trial.
LID - 10.14814/phy2.12693 [doi]
LID - e12693
AB  - To compare the effects of a 3-week multimodal rehabilitation involving supervised 
      high-intensity interval training (HIIT) on female breast cancer survivors with 
      respect to key variables of aerobic fitness, body composition, energy 
      expenditure, cancer-related fatigue, and quality of life to those of a standard 
      multimodal rehabilitation program. A randomized controlled trial design was 
      administered. Twenty-eight women, who had been treated for cancer were randomly 
      assigned to either a group performing exercise of low-to-moderate intensity 
      (LMIE; n = 14) or a group performing high-intensity interval training (HIIT; 
      n = 14) as part of a 3-week multimodal rehabilitation program. No adverse events 
      related to the exercise were reported. Work economy improved following both HIIT 
      and LMIE, with improved peak oxygen uptake following LMIE. HIIT reduced mean 
      total body fat mass with no change in body mass, muscle or fat-free mass (best 
      P < 0.06). LMIE increased muscle and total fat-free body mass. Total energy 
      expenditure (P = 0.45) did not change between the groups, whereas both improved 
      quality of life to a similar high extent and lessened cancer-related fatigue. 
      This randomized controlled study demonstrates that HIIT can be performed by 
      female cancer survivors without adverse health effects. Here, HIIT and LMIE both 
      improved work economy, quality of life and cancer-related fatigue, body 
      composition or energy expenditure. Since the outcomes were similar, but HIIT 
      takes less time, this may be a time-efficient strategy for improving certain 
      aspects of the health of female cancer survivors.
CI  - (c) 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on 
      behalf of the American Physiological Society and The Physiological Society.
FAU - Schmitt, Joachim
AU  - Schmitt J
AD  - Rehaklinik am Kurpark, RehaZentren Baden Wurttemberg gGmbH, Bad Kissingen, 
      Germany.
FAU - Lindner, Nathalie
AU  - Lindner N
AD  - Integrative and Experimental Training Science, Department of Sport Science, 
      Julius-Maximilians-Universitat Wurzburg, Wurzburg, Germany.
FAU - Reuss-Borst, Monika
AU  - Reuss-Borst M
AD  - Rehaklinik am Kurpark, RehaZentren Baden Wurttemberg gGmbH, Bad Kissingen, 
      Germany.
FAU - Holmberg, Hans-Christer
AU  - Holmberg HC
AD  - Swedish Winter Sports Research Centre, Department of Health Sciences, Mid Sweden 
      University, Ostersund, Sweden School of Kinesiology, University of British 
      Columbia, Vancouver, BC, Canada.
FAU - Sperlich, Billy
AU  - Sperlich B
AD  - Integrative and Experimental Training Science, Department of Sport Science, 
      Julius-Maximilians-Universitat Wurzburg, Wurzburg, Germany 
      billy.sperlich@uni-wuerzburg.de.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Physiol Rep
JT  - Physiological reports
JID - 101607800
SB  - IM
MH  - Adult
MH  - Breast Neoplasms/complications/*rehabilitation
MH  - Exercise Therapy/*methods
MH  - Fatigue/epidemiology/etiology
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - *Quality of Life
MH  - Survivors
PMC - PMC4758922
OTO - NOTNLM
OT  - Cancer survivors
OT  - cardiorespiratory fitness
OT  - energy expenditure
OT  - exercise
OT  - rehabilitation
OT  - sense wear
EDAT- 2016/02/13 06:00
MHDA- 2016/02/13 06:01
PMCR- 2016/02/11
CRDT- 2016/02/13 06:00
PHST- 2016/02/13 06:00 [entrez]
PHST- 2016/02/13 06:00 [pubmed]
PHST- 2016/02/13 06:01 [medline]
PHST- 2016/02/11 00:00 [pmc-release]
AID - 4/3/e12693 [pii]
AID - PHY212693 [pii]
AID - 10.14814/phy2.12693 [doi]
PST - ppublish
SO  - Physiol Rep. 2016 Feb;4(3):e12693. doi: 10.14814/phy2.12693.