PMID- 26870286
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1792-1074 (Print)
IS  - 1792-1082 (Electronic)
IS  - 1792-1074 (Linking)
VI  - 11
IP  - 1
DP  - 2016 Jan
TI  - Paraganglioma of the urinary bladder with chromosome duplications detected by 
      fluorescence in situ hybridization in urine exfoliated cells: A case report.
PG  - 795-797
AB  - Paragangliomas of the urinary bladder are rare neoplasms derived from chromaffin 
      tissue with a chromosomal imbalance. Their preoperative diagnosis and assessment 
      of malignant potential remain significant challenges for urologists. The current 
      report presents the case of a 34-year-old male who presented with a history of 
      paroxysmal gross hematuria lasting for 7 months. Chromosome duplications were 
      detected by fluorescence in situ hybridization (FISH) in urine exfoliated cells, 
      and the diagnosis was confirmed by histopathology following a transurethral 
      resection. To the best of our knowledge, this is the first reported case of 
      urinary bladder paraganglioma in which chromosomal duplications were detected by 
      FISH in urine exfoliated cells. This may be helpful to its differential diagnosis 
      and malignant potential determination.
FAU - Yang, Chunguang
AU  - Yang C
AD  - Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
FAU - Liu, Zheng
AU  - Liu Z
AD  - Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
FAU - Lan, Ruzhu
AU  - Lan R
AD  - Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
FAU - Wang, Zhihua
AU  - Wang Z
AD  - Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
FAU - Hu, Zhiquan
AU  - Hu Z
AD  - Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
FAU - Chen, Zhiqiang
AU  - Chen Z
AD  - Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
FAU - Ye, Zhangqun
AU  - Ye Z
AD  - Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
LA  - eng
PT  - Journal Article
DEP - 20151118
PL  - Greece
TA  - Oncol Lett
JT  - Oncology letters
JID - 101531236
PMC - PMC4727148
OTO - NOTNLM
OT  - chromosome duplication
OT  - fluorescence in situ hybridization
OT  - paraganglioma
OT  - urinary bladder
EDAT- 2016/02/13 06:00
MHDA- 2016/02/13 06:01
PMCR- 2015/11/18
CRDT- 2016/02/13 06:00
PHST- 2014/12/11 00:00 [received]
PHST- 2015/10/21 00:00 [accepted]
PHST- 2016/02/13 06:00 [entrez]
PHST- 2016/02/13 06:00 [pubmed]
PHST- 2016/02/13 06:01 [medline]
PHST- 2015/11/18 00:00 [pmc-release]
AID - OL-0-0-3941 [pii]
AID - 10.3892/ol.2015.3941 [doi]
PST - ppublish
SO  - Oncol Lett. 2016 Jan;11(1):795-797. doi: 10.3892/ol.2015.3941. Epub 2015 Nov 18.