PMID- 26872869
OWN - NLM
STAT- MEDLINE
DCOM- 20170117
LR  - 20170117
IS  - 1473-0790 (Electronic)
IS  - 1368-5538 (Linking)
VI  - 19
IP  - 2
DP  - 2016 Jun
TI  - Age and total and free prostate-specific antigen levels for predicting prostate 
      volume in patients with benign prostatic hyperplasia.
PG  - 124-7
LID - 10.3109/13685538.2015.1131260 [doi]
AB  - OBJECTIVES: To investigate the predictive values of free prostate-specific 
      antigen (fPSA), total PSA (tPSA) and age on the prostate volume. METHODS: The 
      data of 2148 patients with lower urinary tract symptoms were analyzed 
      retrospectively. The patients who had transrectal ultrasonography guided 10 core 
      biopsies owing to the findings obtained on digital rectal examination and 
      presence of high PSA levels (PSA = 2.5-10 ng/dl), and proven to have BPH 
      histopathologically were included in the study. Age, tPSA, fPSA and the prostate 
      volumes (PV) of the patients were noted. RESULTS: One thousand patients that 
      fulfilled the inclusion criteria were included in the study. The PV of the 
      patients were significantly correlated with age, tPSA and fPSA (p < 0.001 and 
      r = 0.307, p < 0.001 and r = 0.382, p < 0.001 and r = 0.296, respectively). On 
      linear regression model, fPSA was found as a stronger predictive for PV 
      (AUC = 0.75, p < 0.001) when compared to age (AUC = 0.64, p < 0.001), and tPSA 
      (AUC = 0.69, p = 0.013). CONCLUSIONS: Although tPSA is an important prognostic 
      factor for predicting PV, the predictive value of fPSA is higher. PV can easily 
      be predicted by using age, and serum tPSA and fPSA levels.
FAU - Coban, Soner
AU  - Coban S
AD  - a Department of Urology , Bursa Yuksek Ihtisas Training and Research Hospital , 
      Bursa , Turkey .
FAU - Doluoglu, Omer Gokhan
AU  - Doluoglu OG
AD  - b Department of Urology , Ankara Training and Research Hospital , Ankara , Turkey 
      .
FAU - Keles, Ibrahim
AU  - Keles I
AD  - c Department of Urology , Faculty of Medicine, University of Afyon Kocatepe , 
      Afyon , Turkey , and.
FAU - Demirci, Hakan
AU  - Demirci H
AD  - d Department of Family Medicine , Bursa Yuksek Ihtisas Training and Research 
      Hospital , Bursa , Turkey.
FAU - Turkoglu, Ali Riza
AU  - Turkoglu AR
AD  - a Department of Urology , Bursa Yuksek Ihtisas Training and Research Hospital , 
      Bursa , Turkey .
FAU - Guzelsoy, Muhammet
AU  - Guzelsoy M
AD  - a Department of Urology , Bursa Yuksek Ihtisas Training and Research Hospital , 
      Bursa , Turkey .
FAU - Karalar, Mustafa
AU  - Karalar M
AD  - c Department of Urology , Faculty of Medicine, University of Afyon Kocatepe , 
      Afyon , Turkey , and.
FAU - Demirbas, Murat
AU  - Demirbas M
AD  - a Department of Urology , Bursa Yuksek Ihtisas Training and Research Hospital , 
      Bursa , Turkey .
LA  - eng
PT  - Journal Article
DEP - 20160212
PL  - England
TA  - Aging Male
JT  - The aging male : the official journal of the International Society for the Study 
      of the Aging Male
JID - 9808210
RN  - EC 3.4.21.77 (Prostate-Specific Antigen)
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Humans
MH  - Lower Urinary Tract Symptoms/blood/etiology/pathology
MH  - Male
MH  - Middle Aged
MH  - Organ Size
MH  - Prostate/*pathology
MH  - Prostate-Specific Antigen/*blood
MH  - Prostatic Hyperplasia/*blood/complications/pathology
OTO - NOTNLM
OT  - Benign prostatic hyperplasia
OT  - estimation
OT  - free prostate-specific antigen
OT  - prostate volume
OT  - prostate-specific antigen
EDAT- 2016/02/14 06:00
MHDA- 2017/01/18 06:00
CRDT- 2016/02/14 06:00
PHST- 2016/02/14 06:00 [entrez]
PHST- 2016/02/14 06:00 [pubmed]
PHST- 2017/01/18 06:00 [medline]
AID - 10.3109/13685538.2015.1131260 [doi]
PST - ppublish
SO  - Aging Male. 2016 Jun;19(2):124-7. doi: 10.3109/13685538.2015.1131260. Epub 2016 
      Feb 12.