PMID- 26883531
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160905
LR  - 20181113
IS  - 1879-1123 (Electronic)
IS  - 1044-0305 (Linking)
VI  - 27
IP  - 5
DP  - 2016 May
TI  - Multimodal Vacuum-Assisted Plasma Ion (VaPI) Source with Transmission Mode and 
      Laser Ablation Sampling Capabilities.
PG  - 897-907
LID - 10.1007/s13361-016-1354-8 [doi]
AB  - We have developed a multimodal ion source design that can be configured on the 
      fly for various analysis modes, designed for more efficient and reproducible 
      sampling at the mass spectrometer atmospheric pressure (AP) interface in a number 
      of different applications. This vacuum-assisted plasma ionization (VaPI) source 
      features interchangeable transmission mode and laser ablation sampling 
      geometries. Operating in both AC and DC power regimes with similar results, the 
      ion source was optimized for parameters including helium flow rate and gas 
      temperature using transmission mode to analyze volatile standards and drug 
      tablets. Using laser ablation, matrix effects were studied, and the source was 
      used to monitor the products of model prebiotic synthetic reactions.
FAU - Keelor, Joel D
AU  - Keelor JD
AD  - School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, 
      GA, 30332, USA.
FAU - Farnsworth, Paul B
AU  - Farnsworth PB
AD  - Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT, 
      84602, USA.
FAU - L Weber, Arthur
AU  - L Weber A
AD  - SETI Institute, Mountain View, CA, 94043, USA.
FAU - Abbott-Lyon, Heather
AU  - Abbott-Lyon H
AD  - Department of Chemistry and Biochemistry, Kennesaw State University, Kennesaw, 
      GA, 30144, USA.
FAU - Fernandez, Facundo M
AU  - Fernandez FM
AD  - School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, 
      GA, 30332, USA. facundo.fernandez@chemistry.gatech.edu.
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20160216
PL  - United States
TA  - J Am Soc Mass Spectrom
JT  - Journal of the American Society for Mass Spectrometry
JID - 9010412
OTO - NOTNLM
OT  - Ambient plasma ionization
OT  - Laser ablation
OT  - Mass spectrometry
OT  - Prebiotic chemistry
OT  - Transmission mode
EDAT- 2016/02/18 06:00
MHDA- 2016/02/18 06:01
CRDT- 2016/02/18 06:00
PHST- 2015/09/18 00:00 [received]
PHST- 2016/01/25 00:00 [accepted]
PHST- 2016/01/22 00:00 [revised]
PHST- 2016/02/18 06:00 [entrez]
PHST- 2016/02/18 06:00 [pubmed]
PHST- 2016/02/18 06:01 [medline]
AID - 10.1007/s13361-016-1354-8 [pii]
AID - 10.1007/s13361-016-1354-8 [doi]
PST - ppublish
SO  - J Am Soc Mass Spectrom. 2016 May;27(5):897-907. doi: 10.1007/s13361-016-1354-8. 
      Epub 2016 Feb 16.